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    RCE1 RUB1 conjugating enzyme 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829833, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RCE1
    Official Full Name
    RUB1 conjugating enzyme 1
    Primary source
    TAIR:AT4G36800
    Locus tag
    AT4G36800
    See related
    Araport:AT4G36800
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AP22.40; AP22_40; RUB1 conjugating enzyme 1
    Summary
    RUB1 conjugating enzyme that conjugates CUL1 and is involved in auxin response and embryogenesis. RCE1 protein physically interacts with RBX1, which may be the E3 for CUL1.
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    Genomic context

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    See RCE1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    6
    Sequence:
    Chromosome: 4; NC_003075.7 (17340932..17343035, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Major facilitator superfamily protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene geranylgeranyl pyrophosphate synthase 1 Neighboring gene calcium uniporter (DUF607)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis cullin AtCUL1 is modified by the ubiquitin-related protein RUB1. del Pozo JC, et al. Proc Natl Acad Sci U S A, 1999 Dec 21. PMID 10611386, Free PMC Article
    2. The RUB/Nedd8 conjugation pathway is required for early development in Arabidopsis. Dharmasiri S, et al. EMBO J, 2003 Apr 15. PMID 12682009, Free PMC Article
    3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001160817.1
    NM_119844.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables NEDD8 transferase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ubiquitin-like protein transferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo development ending in seed dormancy IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in protein neddylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to auxin IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    RUB1 conjugating enzyme 1
    NP_001154289.1
    • RUB1 conjugating enzyme 1 (RCE1); CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608), RUB1 conjugating enzyme Ubc12 (InterPro:IPR015580); BEST Arabidopsis thaliana protein match is: Ubiquitin-conjugating enzyme family protein (TAIR:AT2G18600.1); Has 8473 Blast hits to 8470 proteins in 386 species: Archae - 0; Bacteria - 0; Metazoa - 3871; Fungi - 1731; Plants - 1533; Viruses - 20; Other Eukaryotes - 1318 (source: NCBI BLink).
    NP_568008.4
    • RUB1 conjugating enzyme 1 (RCE1); CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608), RUB1 conjugating enzyme Ubc12 (InterPro:IPR015580); BEST Arabidopsis thaliana protein match is: Ubiquitin-conjugating enzyme family protein (TAIR:AT2G18600.1); Has 8473 Blast hits to 8470 proteins in 386 species: Archae - 0; Bacteria - 0; Metazoa - 3871; Fungi - 1731; Plants - 1533; Viruses - 20; Other Eukaryotes - 1318 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      17340932..17343035 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119844.6 → NP_568008.4  RUB1 conjugating enzyme 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568008.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23202, Q0WLB1, Q9SDY5
      UniProtKB/TrEMBL
      A0A178UX02, A0A5S9XZJ0
      Conserved Domains (1) summary
      pfam00179
      Location:34 → 170
      UQ_con; Ubiquitin-conjugating enzyme

    2. NM_001160817.1 → NP_001154289.1  RUB1 conjugating enzyme 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001154289.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23202, Q0WLB1, Q9SDY5
      UniProtKB/TrEMBL
      A0A178UX02, A0A5S9XZJ0
      Conserved Domains (1) summary
      pfam00179
      Location:34 → 170
      UQ_con; Ubiquitin-conjugating enzyme
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SDY5.1

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