Rnf138l1 ring finger protein 138 like 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Rnf138l1provided by RGD
Official Full Name: ring finger protein 138 like 1provided by RGD
Primary source: RGD:1565844
See related: EnsemblRapid:ENSRNOG00000004120 AllianceGenome:RGD:1565844
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1565844
Summary: Predicted to enable single-stranded DNA binding activity and ubiquitin protein ligase activity. Predicted to be involved in DNA double-strand break processing involved in repair via single-strand annealing and double-strand break repair via homologous recombination. Predicted to be active in site of double-strand break. Orthologous to human RNF138 (ring finger protein 138). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: mouse all
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Genomic context

Location:: Xq14

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	X	NC_086039.1 (34371379..34372452)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	X	NC_051356.1 (30739541..30740614)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	X	NC_005120.4 (32495573..32496646)

Chromosome X - NC_086039.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables single-stranded DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin protein ligase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in DNA double-strand break processing involved in repair via single-strand annealing	IBA Inferred from Biological aspect of Ancestor more info
involved_in double-strand break repair via homologous recombination	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein ubiquitination	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in site of double-strand break	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: E3 ubiquitin-protein ligase RNF138-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001108255.2 → NP_001101725.1 E3 ubiquitin-protein ligase RNF138-like

See identical proteins and their annotated locations for NP_001101725.1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000021

UniProtKB/TrEMBL

A6K2M6, D3ZI70

Related

ENSRNOP00000020999.7, ENSRNOT00000020999.8

Conserved Domains (2) summary

cd00162
Location:18 → 61

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

pfam05605
Location:158 → 217

zf-Di19; Drought induced 19 protein (Di19), zinc-binding