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    isy1 ISY1 splicing factor homolog [ Danio rerio (zebrafish) ]

    Gene ID: 570205, updated on 9-Dec-2024

    Summary

    Official Symbol
    isy1provided by ZNC
    Official Full Name
    ISY1 splicing factor homologprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5864
    See related
    Ensembl:ENSDARG00000063466 AllianceGenome:ZFIN:ZDB-GENE-030131-5864
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:7159238; wu:fc23h01; wu:fi21h07; zgc:136785
    Summary
    Predicted to be involved in generation of catalytic spliceosome for second transesterification step and mRNA 3'-splice site recognition. Predicted to be located in nucleus. Predicted to be part of Prp19 complex and spliceosomal complex. Orthologous to several human genes including ISY1 (ISY1 splicing factor homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See isy1 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (474433..486532, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (447941..459808, complement)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene RAB43, member RAS oncogene family Neighboring gene zgc:77375 Neighboring gene CCHC-type zinc finger, nucleic acid binding protein b Neighboring gene Raf-1 proto-oncogene, serine/threonine kinase b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC136785

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    part_of Prp19 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of post-mRNA release spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of post-spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    pre-mRNA-splicing factor ISY1 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083563.2NP_001077032.1  pre-mRNA-splicing factor ISY1 homolog

      See identical proteins and their annotated locations for NP_001077032.1

      Status: VALIDATED

      Source sequence(s)
      CR855375
      UniProtKB/TrEMBL
      A0A8M1NCD6, A4FUN5
      Related
      ENSDARP00000087580.3, ENSDART00000093148.5
      Conserved Domains (1) summary
      pfam06246
      Location:1266
      Isy1; Isy1-like splicing family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      474433..486532 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)