twist3 twist3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: twist3provided by ZNC
Official Full Name: twist3provided by ZNC
Primary source: ZFIN:ZDB-GENE-000210-7
See related: Ensembl:ENSDARG00000019646 AllianceGenome:ZFIN:ZDB-GENE-000210-7
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: twist2; twist-2; hm:zeh0190
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in developmental process and regulation of transcription by RNA polymerase II. Is expressed in several structures, including dermis; fin; fin bud; lateral plate mesoderm; and vertical myoseptum. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 23

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (2669..9339)
105	previous assembly	GRCz10 (GCF_000002035.5)	23	NC_007134.6 (2669..9339)

Chromosome 23 - NC_007134.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Twist3 is required for dedifferentiation during extraocular muscle regeneration in adult zebrafish
Title: Twist3 is required for dedifferentiation during extraocular muscle regeneration in adult zebrafish.
analysis of embryonic twist mRNA expression profiles in zebrafish
Title: Four twist genes in zebrafish, four expression patterns.

Submit: New GeneRIF Correction

General gene information

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Markers

z6742 (e-PCR), detects polymorphism
- UniSTS:204913

Z5265 (e-PCR)
- UniSTS:35464

twist2 (e-PCR), detects polymorphism
- UniSTS:205474

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in developmental process	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: twist3

Names: Dermo1; twist2l

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.