sec11a SEC11 homolog A, signal peptidase complex subunit [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: sec11aprovided by ZNC
Official Full Name: SEC11 homolog A, signal peptidase complex subunitprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040718-227
See related: Ensembl:ENSDARG00000008936 AllianceGenome:ZFIN:ZDB-GENE-040718-227
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: sec11; sec11l1; zgc:92805
Summary: Predicted to enable peptidase activity. Predicted to be involved in signal peptide processing. Predicted to act upstream of or within proteolysis. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be part of signal peptidase complex. Orthologous to human SEC11A (SEC11 homolog A, signal peptidase complex subunit). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 18

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	18	NC_007129.7 (26788091..26797699, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	18	NC_007129.6 (26805713..26815321, complement)

Chromosome 18 - NC_007129.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables peptidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables peptidase activity	IEA Inferred from Electronic Annotation more info
enables serine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within proteolysis	IEA Inferred from Electronic Annotation more info
involved_in signal peptide processing	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within signal peptide processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
part_of signal peptidase complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: signal peptidase complex catalytic subunit SEC11A

Names: SEC11-like 1

NP_001002521.1

EC 3.4.21.89

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002521.2 → NP_001002521.1 signal peptidase complex catalytic subunit SEC11A

See identical proteins and their annotated locations for NP_001002521.1

Status: PROVISIONAL

Source sequence(s)

BC076276

UniProtKB/TrEMBL

Q6DGR3

Related

ENSDARP00000009538.5, ENSDART00000008013.6

Conserved Domains (1) summary

cl10465
Location:38 → 150

Peptidase_S24_S26; The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the ...