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    nxf1a nuclear RNA export factor 1a [ Danio rerio (zebrafish) ]

    Gene ID: 751719, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nxf1aprovided by ZNC
    Official Full Name
    nuclear RNA export factor 1aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060825-299
    See related
    Ensembl:ENSDARG00000086017 AllianceGenome:ZFIN:ZDB-GENE-060825-299
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:153681
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in poly(A)+ mRNA export from nucleus. Predicted to act upstream of or within mRNA export from nucleus. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Orthologous to human NXF1 (nuclear RNA export factor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See nxf1a in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (8893487..8940478, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (8587471..8634464, complement)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene tRNA methyltransferase activator subunit 11-2 Neighboring gene autophagy related 2A Neighboring gene uncharacterized LOC137487565 Neighboring gene ribosomal protein S6 kinase a, like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Processing of fish Ig heavy chain transcripts: diverse splicing patterns and unusual nonsense mediated decay. Quiniou SM, et al. Dev Comp Immunol, 2011 Sep. PMID 21168434
    2. Transcriptomic analyses reveal novel genes with sexually dimorphic expression in the zebrafish gonad and brain. Sreenivasan R, et al. PLoS One, 2008 Mar 12. PMID 18335061, Free PMC Article
    3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC153681

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within mRNA export from nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within mRNA transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC751719

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045429.1 → NP_001038894.1  uncharacterized protein LOC751719

      See identical proteins and their annotated locations for NP_001038894.1

      Status: PREDICTED

      Source sequence(s)
      BC122378
      UniProtKB/TrEMBL
      Q0P3Y8
      Related
      ENSDARP00000109457.1, ENSDART00000129030.3
      Conserved Domains (5) summary
      cd00780
      Location:413 → 561
      NTF2; Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many ...
      sd00035
      Location:249 → 291
      LRR_NTF; leucine-rich repeat [structural motif]
      pfam09162
      Location:142 → 223
      Tap-RNA_bind; Tap, RNA-binding
      pfam12799
      Location:290 → 336
      LRR_4; Leucine Rich repeats (2 copies)
      cl21463
      Location:579 → 610
      UBA_like_SF; UBA domain-like superfamily

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      8893487..8940478 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009307743.4 → XP_009306018.1  uncharacterized protein LOC751719 isoform X1

      UniProtKB/TrEMBL
      A0A8M3AZK2
      Conserved Domains (5) summary
      smart00804
      Location:579 → 641
      TAP_C; C-terminal domain of vertebrate Tap protein
      cd00780
      Location:413 → 561
      NTF2; Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many ...
      sd00035
      Location:249 → 291
      LRR_NTF; leucine-rich repeat [structural motif]
      pfam09162
      Location:142 → 223
      Tap-RNA_bind; Tap, RNA-binding
      pfam12799
      Location:290 → 336
      LRR_4; Leucine Rich repeats (2 copies)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394892.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      254788..259076 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394893.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      1..30981 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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