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    nudt5 nudix (nucleoside diphosphate linked moiety X)-type motif 5 [ Danio rerio (zebrafish) ]

    Gene ID: 415176, updated on 9-Dec-2024

    Summary

    Official Symbol
    nudt5provided by ZNC
    Official Full Name
    nudix (nucleoside diphosphate linked moiety X)-type motif 5provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040625-63
    See related
    Ensembl:ENSDARG00000078073 AllianceGenome:ZFIN:ZDB-GENE-040625-63
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:86930; wu:fe48a12
    Summary
    Predicted to enable ADP-ribose diphosphatase activity. Predicted to be involved in nucleoside phosphate metabolic process and ribose phosphate metabolic process. Predicted to be active in nucleus. Orthologous to human NUDT5 (nudix hydrolase 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See nudt5 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (7870384..7876005, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (7861755..7867376, complement)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene upper zone of growth plate and cartilage matrix associated a Neighboring gene minichromosome maintenance 10 replication initiation factor Neighboring gene cell division cycle 123 homolog (S. cerevisiae) Neighboring gene calcium/calmodulin-dependent protein kinase 1Da

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ADP-ribose diphosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ADP-ribose diphosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in nucleoside phosphate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ribose phosphate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    ADP-sugar pyrophosphatase
    NP_001002086.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002086.1NP_001002086.1  ADP-sugar pyrophosphatase

      See identical proteins and their annotated locations for NP_001002086.1

      Status: PROVISIONAL

      Source sequence(s)
      BC071544
      UniProtKB/TrEMBL
      A0A8M1MZV8, Q6IQ66
      Related
      ENSDARP00000099881.2, ENSDART00000109252.4
      Conserved Domains (1) summary
      cd03424
      Location:58202
      ADPRase_NUDT5; ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+, ...

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      7870384..7876005 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)