bmb brambleberry [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: bmbprovided by ZNC
Official Full Name: brambleberryprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-5577
See related: Ensembl:ENSDARG00000096603 AllianceGenome:ZFIN:ZDB-GENE-030131-5577
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fi04f09; wu:fi04f09
Summary: Involved in pronuclear fusion. Acts upstream of or within karyomere membrane fusion. Predicted to be located in nuclear membrane. Is expressed in several structures, including blastomere. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 25

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	25	NC_007136.7 (36292465..36310015)
105	previous assembly	GRCz10 (GCF_000002035.5)	25	NC_007136.6 (35742746..35760296)

Chromosome 25 - NC_007136.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Study identified brambleberry, a maternal-effect zebrafish mutant that disrupts karyomere fusion, resulting in formation of multiple micronuclei. As karyomeres form, Brambleberry protein localizes to the nuclear envelope, with prominent puncta evident near karyomere-karyomere interfaces corresponding to membrane fusion sites.
Title: Dynamic assembly of brambleberry mediates nuclear envelope fusion during early development.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

fi76d05.x1 (e-PCR)
- UniSTS:198007

fi04f09.x1 (e-PCR)
- UniSTS:204422

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within karyogamy	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within karyomere membrane fusion	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within pronuclear fusion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in pronuclear fusion	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in nuclear membrane	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: protein brambleberry

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001270554.1 → NP_001257483.1 protein brambleberry precursor

See identical proteins and their annotated locations for NP_001257483.1

Status: PROVISIONAL

Source sequence(s)

JX073281

UniProtKB/Swiss-Prot

I6V1W0

Related

ENSDARP00000126692.1, ENSDART00000152329.3

Conserved Domains (1) summary

cl00459
Location:224 → 290

MIT_CorA-like; metal ion transporter CorA-like divalent cation transporter superfamily