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    anxa1c annexin A1c [ Danio rerio (zebrafish) ]

    Gene ID: 494158, updated on 4-Jan-2025

    Summary

    Official Symbol
    anxa1cprovided by ZNC
    Official Full Name
    annexin A1cprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5274
    See related
    Ensembl:ENSDARG00000104359 AllianceGenome:ZFIN:ZDB-GENE-030131-5274
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    anx1c; ANX Ic; sb:cb276; zgc:86853; wu:fa22e03; wu:fj17g03; zgc:123146
    Summary
    Predicted to enable calcium-dependent phospholipid binding activity and phosphatidylserine binding activity. Predicted to be involved in cellular response to glucocorticoid stimulus; phagocytosis; and signal transduction. Predicted to be active in several cellular components, including nucleus; plasma membrane; and vesicle membrane. Is expressed in EVL and periderm. Human ortholog(s) of this gene implicated in brain ischemia and pancreatic cancer. Orthologous to human ANXA1 (annexin A1). [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

    See anxa1c in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (65009764..65021736, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (64320767..64332797, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101882342 Neighboring gene annexin A1d Neighboring gene annexin A1b Neighboring gene peptidase, mitochondrial processing subunit alpha

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC123146

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables calcium-dependent phospholipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables calcium-dependent phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidylserine binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in cellular response to glucocorticoid stimulus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in phagocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    annexin A1c
    Names
    annexin 1c

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_181760.2NP_861425.1  annexin A1c

      See identical proteins and their annotated locations for NP_861425.1

      Status: PROVISIONAL

      Source sequence(s)
      AY178795
      UniProtKB/TrEMBL
      A0A8M1PAK9, Q804H0
      Related
      ENSDARP00000139017.1, ENSDART00000166183.2
      Conserved Domains (1) summary
      pfam00191
      Location:272337
      Annexin; Annexin

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      65009764..65021736 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005165606.5XP_005165663.1  annexin A1c isoform X1

      See identical proteins and their annotated locations for XP_005165663.1

      UniProtKB/TrEMBL
      A0A8M1PAK9, Q804H0
      Related
      ENSDARP00000137943.1, ENSDART00000162368.2
      Conserved Domains (1) summary
      pfam00191
      Location:272337
      Annexin; Annexin