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    ctnnbl1 catenin, beta like 1 [ Danio rerio (zebrafish) ]

    Gene ID: 393840, updated on 4-Jan-2025

    Summary

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    Official Symbol
    ctnnbl1provided by ZNC
    Official Full Name
    catenin, beta like 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1850
    See related
    Ensembl:ENSDARG00000011958 AllianceGenome:ZFIN:ZDB-GENE-040426-1850
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:77673
    Summary
    Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Human ortholog(s) of this gene implicated in colorectal cancer; morbid obesity; and primary immunodeficiency disease. Orthologous to human CTNNBL1 (catenin beta like 1). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See ctnnbl1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (53720028..53815533)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (54268039..54363544)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene chemokine (C-C motif) ligand 25a Neighboring gene RAN binding protein 3b Neighboring gene neurturin Neighboring gene calcyphosine-like a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Many genes in fish have species-specific asymmetric rates of molecular evolution. Steinke D, et al. BMC Genomics, 2006 Feb 8. PMID 16466575, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC77673

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    beta-catenin-like protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200866.1 → NP_957160.1  beta-catenin-like protein 1

      See identical proteins and their annotated locations for NP_957160.1

      Status: PROVISIONAL

      Source sequence(s)
      BC063231
      UniProtKB/TrEMBL
      A0A0R4INT5, A0A8M1PI26, Q6P4V4
      Related
      ENSDARP00000136166.2, ENSDART00000170799.2
      Conserved Domains (2) summary
      cd00020
      Location:125 → 220
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam08216
      Location:61 → 159
      CTNNBL; Catenin-beta-like, Arm-motif containing nuclear

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      53720028..53815533
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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