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    med16 mediator complex subunit 16 [ Danio rerio (zebrafish) ]

    Gene ID: 570199, updated on 9-Dec-2024

    Summary

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    Official Symbol
    med16provided by ZNC
    Official Full Name
    mediator complex subunit 16provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090306-4
    See related
    Ensembl:ENSDARG00000040779 AllianceGenome:ZFIN:ZDB-GENE-090306-4
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    lppr3b; fc22c09; fc29h12; wu:fc22c09; wu:fc29h12
    Summary
    Predicted to be involved in positive regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of mediator complex. Orthologous to human MED16 (mediator complex subunit 16). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See med16 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (14104478..14143702)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (14046780..14086043)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103911814 Neighboring gene transmembrane protein 259 Neighboring gene phospholipid phosphatase related 3b Neighboring gene paralemmin 1a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mediator complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mediator of RNA polymerase II transcription subunit 16
    Names
    lipid phosphate phosphatase-related protein type 3b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001199872.1 → NP_001186801.1  mediator of RNA polymerase II transcription subunit 16

      Status: VALIDATED

      Source sequence(s)
      BX000430
      UniProtKB/TrEMBL
      A0A2R8Q3Q1, A0A8M1NWI6
      Related
      ENSDARP00000145459.1, ENSDART00000186575.1
      Conserved Domains (4) summary
      smart00320
      Location:69 → 99
      WD40; WD40 repeats
      COG2319
      Location:51 → 235
      WD40; WD40 repeat [General function prediction only]
      pfam11635
      Location:113 → 826
      Med16; Mediator complex subunit 16
      sd00039
      Location:75 → 116
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      14104478..14143702
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005155957.4 → XP_005156014.1  mediator of RNA polymerase II transcription subunit 16 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B2V1, E7F602
      Related
      ENSDARP00000059751.4, ENSDART00000059752.6
      Conserved Domains (4) summary
      smart00320
      Location:83 → 113
      WD40; WD40 repeats
      COG2319
      Location:25 → 249
      WD40; WD40 repeat [General function prediction only]
      pfam11635
      Location:127 → 840
      Med16; Mediator complex subunit 16
      sd00039
      Location:89 → 130
      7WD40; WD40 repeat [structural motif]

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394806.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      13716..52939
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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