ip6k2a inositol hexakisphosphate kinase 2a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ip6k2aprovided by ZNC
Official Full Name: inositol hexakisphosphate kinase 2aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-760
See related: Ensembl:ENSDARG00000008310 AllianceGenome:ZFIN:ZDB-GENE-030131-760
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ihpk2; ip6k2; cb1087; wu:fb47g07; wu:fi24d03
Summary: Predicted to enable inositol hexakisphosphate kinase activity. Acts upstream of or within positive regulation of smoothened signaling pathway. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including axis; immature eye; nervous system; pronephric duct; and segmental plate. Orthologous to human IP6K2 (inositol hexakisphosphate kinase 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 6

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (42409249..42418165, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (42411713..42420629, complement)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

IP6K2 is a positive regulator of Hh signaling.
Title: Inositol hexakisphosphate kinase-2 acts as an effector of the vertebrate Hedgehog pathway.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

fk62f02.x1 (e-PCR)
- UniSTS:201323

fi24d03.x1 (e-PCR)
- UniSTS:197084

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables inositol hexakisphosphate kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity, transferring phosphorus-containing groups	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in inositol phosphate biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within inositol phosphate biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in phosphatidylinositol phosphate biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of smoothened signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: inositol hexakisphosphate kinase 2a

Names: inositol hexaphosphate kinase 2; inositol hexaphosphate kinase 2a

NP_958878.1

EC 2.7.4.21

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.