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    nobox NOBOX oogenesis homeobox [ Danio rerio (zebrafish) ]

    Gene ID: 334444, updated on 9-Dec-2024

    Summary

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    Official Symbol
    noboxprovided by ZNC
    Official Full Name
    NOBOX oogenesis homeoboxprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-6376
    See related
    AllianceGenome:ZFIN:ZDB-GENE-030131-6376
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fi69e09; wu:fi69e09
    Summary
    Predicted to enable DNA binding activity and DNA-binding transcription factor activity. Acts upstream of or within regulation of female gonad development and regulation of ovarian follicle development. Predicted to be located in nucleus. Is expressed in ovary and testis. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 5. Orthologous to human NOBOX (NOBOX oogenesis homeobox). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    See nobox in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) Unplaced Scaffold NW_003335779.1 (38672..50445)
    105 previous assembly GRCz10 (GCF_000002035.5) Unplaced Scaffold NW_003335779.1 (38674..47398)

    NW_003335779.1Genomic Context describing neighboring genes Neighboring gene syndecan 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Loss of Nobox prevents ovarian differentiation from juvenile ovaries in zebrafish. Qin M, et al. Biol Reprod, 2022 Jun 13. PMID 35157068
    2. Genetic evidence for differential functions of figla and nobox in zebrafish ovarian differentiation and folliculogenesis. Wu K, et al. Commun Biol, 2023 Nov 21. PMID 37990081, Free PMC Article
    3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of female gonad development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of ovarian follicle development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    NOBOX oogenesis homeobox; homeobox protein NOBOX

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NW_003335779.1 Reference GRCz11 Primary Assembly

      Range
      38672..50445
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021470840.2 → XP_021326515.2  homeobox protein NOBOX

    Nucleotide Protein Strain
    Heading Accession and Version

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