U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    krt1-19d keratin, type 1, gene 19d [ Danio rerio (zebrafish) ]

    Gene ID: 664718, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    krt1-19dprovided by ZNC
    Official Full Name
    keratin, type 1, gene 19dprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060316-1
    See related
    Ensembl:ENSDARG00000023082 AllianceGenome:ZFIN:ZDB-GENE-060316-1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable structural molecule activity. Predicted to be located in intermediate filament. Predicted to be active in cytoskeleton. Is expressed in epidermis. Human ortholog(s) of this gene implicated in several diseases, including corneal dystrophy (multiple); ectodermal dysplasia (multiple); epidermolytic hyperkeratosis (multiple); focal nonepidermolytic palmoplantar keratoderma 1; and pachyonychia congenita. Orthologous to several human genes including KRT13 (keratin 13); KRT14 (keratin 14); and KRT15 (keratin 15). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See krt1-19d in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (5324653..5332808, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (5408173..5416336, complement)

    Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene si:dkeyp-113d7.10 Neighboring gene si:dkeyp-113d7.1 Neighboring gene keratin, type 1, 19e Neighboring gene keratin 92

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. FGF and canonical Wnt signaling cooperate to induce paraxial mesoderm from tailbud neuromesodermal progenitors through regulation of a two-step epithelial to mesenchymal transition. Goto H, et al. Development, 2017 Apr 15. PMID 28242612, Free PMC Article
    2. Independent expansion of the keratin gene family in teleostean fish and mammals: an insight from phylogenetic analysis and radiation hybrid mapping of keratin genes in zebrafish. Krushna Padhi B, et al. Gene, 2006 Mar 1. PMID 16297574
    3. Zebrafish: a model system to study heritable skin diseases. Li Q, et al. J Invest Dermatol, 2011 Mar. PMID 21191402, Free PMC Article
    4. Cellular diversity of the regenerating caudal fin. Hou Y, et al. Sci Adv, 2020 Aug. PMID 32851162, Free PMC Article
    5. Tissue-Specific Transcriptomes Reveal Gene Expression Trajectories in Two Maturing Skin Epithelial Layers in Zebrafish Embryos. Cokus SJ, et al. G3 (Bethesda), 2019 Oct 7. PMID 31431477, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in intermediate filament IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    keratin, type 1, gene 19d; keratin, type I cytoskeletal 13
    Names
    keratin like
    krtl
    krtt1c19d

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007130.7 Reference GRCz11 Primary Assembly

      Range
      5324653..5332808 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001342753.9 → XP_001342789.4  keratin, type I cytoskeletal 13

      UniProtKB/TrEMBL
      A0A8M1PV49, Q1LXK0
      Related
      ENSDARP00000011549.8, ENSDART00000010373.9
      Conserved Domains (1) summary
      pfam00038
      Location:72 → 380
      Filament; Intermediate filament protein
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools