pde9aa phosphodiesterase 9aa [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: pde9aaprovided by ZNC
Official Full Name: phosphodiesterase 9aaprovided by ZNC
Primary source: ZFIN:ZDB-GENE-130920-1
See related: Ensembl:ENSDARG00000060280 AllianceGenome:ZFIN:ZDB-GENE-130920-1
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: pde9a; si:ch211-140m22.4
Summary: Predicted to enable 3',5'-cyclic-AMP phosphodiesterase activity and 3',5'-cyclic-GMP phosphodiesterase activity. Predicted to be involved in cAMP-mediated signaling and cGMP catabolic process. Predicted to act upstream of or within signal transduction. Is expressed in several structures, including heart; integument; liver; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human PDE9A (phosphodiesterase 9A). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	9	NC_007120.7 (19421673..19477253)
105	previous assembly	GRCz10 (GCF_000002035.5)	9	NC_007120.6 (19610789..19666390)

Chromosome 9 - NC_007120.7 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Dual roles of PDE9a in meiotic maturation of zebrafish oocytes.
Title: Dual roles of PDE9a in meiotic maturation of zebrafish oocytes.

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables 3',5'-cyclic-AMP phosphodiesterase activity	IBA Inferred from Biological aspect of Ancestor more info
enables 3',5'-cyclic-GMP phosphodiesterase activity	IBA Inferred from Biological aspect of Ancestor more info
enables 3',5'-cyclic-nucleotide phosphodiesterase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables phosphoric diester hydrolase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cAMP-mediated signaling	IBA Inferred from Biological aspect of Ancestor more info
involved_in cGMP catabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Preferred Names: high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

XP_009302928.1

XP_021334564.1

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The following sections contain reference sequences that belong to a specific genome build. Explain