U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    mprip myosin phosphatase Rho interacting protein [ Danio rerio (zebrafish) ]

    Gene ID: 558831, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    mpripprovided by ZNC
    Official Full Name
    myosin phosphatase Rho interacting proteinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-4471
    See related
    Ensembl:ENSDARG00000102081 AllianceGenome:ZFIN:ZDB-GENE-030131-4471
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fd08a03; zgc:175222
    Summary
    Predicted to enable actin filament binding activity. Predicted to be active in actin cytoskeleton. Is expressed in habenula and ventral habenular nucleus. Orthologous to human MPRIP (myosin phosphatase Rho interacting protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See mprip in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (465680..528026)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (459673..522085)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene heparan sulfate (glucosamine) 3-O-sulfotransferase 3-like Neighboring gene dehydrogenase/reductase (SDR family) member 7Cb Neighboring gene si:dkey-94l16.4 Neighboring gene brain specific kinase 146

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Gypenosides Alleviate Cone Cell Death in a Zebrafish Model of Retinitis Pigmentosa. Li X, et al. Antioxidants (Basel), 2021 Jun 29. PMID 34209942, Free PMC Article
    2. Comprehensive Identification and Spatial Mapping of Habenular Neuronal Types Using Single-Cell RNA-Seq. Pandey S, et al. Curr Biol, 2018 Apr 2. PMID 29576475, Free PMC Article
    3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    General protein information

    Go to the top of the page Help
    Preferred Names
    myosin phosphatase Rho-interacting protein; myosin phosphatase-Rho interacting protein

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      465680..528026
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009306361.4 → XP_009304636.1  myosin phosphatase Rho-interacting protein isoform X1

      UniProtKB/TrEMBL
      A0A8M3BDY0
      Conserved Domains (4) summary
      cd01236
      Location:16 → 151
      PH_RIP; Rho-Interacting Protein Pleckstrin homology (PH) domain
      cd13275
      Location:433 → 533
      PH_M-RIP; Myosin phosphatase-RhoA Interacting Protein Pleckstrin homology (PH) domain
      TIGR02168
      Location:908 → 1663
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam00169
      Location:433 → 526
      PH; PH domain

    2. XM_068224680.1 → XP_068080781.1  myosin phosphatase Rho-interacting protein isoform X3

      UniProtKB/TrEMBL
      A0A0R4IE40, A0A8M3AXX8
      Related
      ENSDARP00000133666.1, ENSDART00000160252.2

    3. XM_021480197.2 → XP_021335872.1  myosin phosphatase Rho-interacting protein isoform X2

      UniProtKB/TrEMBL
      A0A8M9Q8Q2
      Conserved Domains (4) summary
      cd01236
      Location:16 → 151
      PH_RIP; Rho-Interacting Protein Pleckstrin homology (PH) domain
      cd13275
      Location:433 → 533
      PH_M-RIP; Myosin phosphatase-RhoA Interacting Protein Pleckstrin homology (PH) domain
      cl25732
      Location:908 → 1663
      SMC_N; RecF/RecN/SMC N terminal domain
      cl28033
      Location:163 → 393
      Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

    4. XM_021480198.2 → XP_021335873.1  myosin phosphatase Rho-interacting protein isoform X2

      UniProtKB/TrEMBL
      A0A8M9Q8Q2
      Conserved Domains (4) summary
      cd01236
      Location:16 → 151
      PH_RIP; Rho-Interacting Protein Pleckstrin homology (PH) domain
      cd13275
      Location:433 → 533
      PH_M-RIP; Myosin phosphatase-RhoA Interacting Protein Pleckstrin homology (PH) domain
      cl25732
      Location:908 → 1663
      SMC_N; RecF/RecN/SMC N terminal domain
      cl28033
      Location:163 → 393
      Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001111159.1: Suppressed sequence

      Description
      NM_001111159.1: This RefSeq was temporarily suppressed because the CDS was partial.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials