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    snap23.1 synaptosome associated protein 23.1 [ Danio rerio (zebrafish) ]

    Gene ID: 393159, updated on 9-Dec-2024

    Summary

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    Official Symbol
    snap23.1provided by ZNC
    Official Full Name
    synaptosome associated protein 23.1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-883
    See related
    Ensembl:ENSDARG00000012874 AllianceGenome:ZFIN:ZDB-GENE-040426-883
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:56072
    Summary
    Predicted to enable SNAP receptor activity and syntaxin binding activity. Predicted to be involved in synaptic vesicle fusion to presynaptic active zone membrane and synaptic vesicle priming. Predicted to be located in neuron projection and synapse. Predicted to be part of SNARE complex. Predicted to be active in plasma membrane. Orthologous to human SNAP23 (synaptosome associated protein 23). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See snap23.1 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (33415344..33430693)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (33462817..33478178)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene zgc:162964 Neighboring gene epithelial cell transforming 2 like Neighboring gene coiled-coil domain containing 28A Neighboring gene synaptosome associated protein 23.2 Neighboring gene uncharacterized LOC137488121

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A genetic model of CEDNIK syndrome in zebrafish highlights the role of the SNARE protein Snap29 in neuromotor and epidermal development. Mastrodonato V, et al. Sci Rep, 2019 Feb 4. PMID 30718891, Free PMC Article
    2. Evolutionary recruitment of flexible Esrp-dependent splicing programs into diverse embryonic morphogenetic processes. Burguera D, et al. Nat Commun, 2017 Nov 27. PMID 29180615, Free PMC Article
    3. In vivo imaging of molecular interactions at damaged sarcolemma. Roostalu U, et al. Dev Cell, 2012 Mar 13. PMID 22421042
    4. Coherent but overlapping expression of microRNAs and their targets during vertebrate development. Shkumatava A, et al. Genes Dev, 2009 Feb 15. PMID 19240133, Free PMC Article
    5. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC56072

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables SNAP receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables syntaxin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in synaptic vesicle fusion to presynaptic active zone membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in synaptic vesicle priming IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of SNARE complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    synaptosome associated protein 23.1
    Names
    synaptosomal-associated protein 23.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200190.1 → NP_956484.1  synaptosome associated protein 23.1

      See identical proteins and their annotated locations for NP_956484.1

      Status: PROVISIONAL

      Source sequence(s)
      BC045896
      UniProtKB/TrEMBL
      A0A0R4IW20, A0A8N7XJG5, F6NZC2, Q7ZVE4
      Related
      ENSDARP00000014467.6, ENSDART00000025501.9
      Conserved Domains (3) summary
      cd15884
      Location:154 → 212
      SNARE_SNAP23C; C-terminal SNARE motif of SNAP23
      cd15889
      Location:11 → 75
      SNARE_SNAP25N_23N; N-terminal SNARE motif of SNAP25 and SNAP23
      pfam00835
      Location:86 → 152
      SNAP-25; SNAP-25 family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      33415344..33430693
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005158725.5 → XP_005158782.1  synaptosome associated protein 23.1 isoform X1

      See identical proteins and their annotated locations for XP_005158782.1

      UniProtKB/TrEMBL
      A0A2R8RXS8, A0A8M2B5L7
      Related
      ENSDARP00000155545.1, ENSDART00000183169.1
      Conserved Domains (3) summary
      cd15884
      Location:177 → 235
      SNARE_SNAP23C; C-terminal SNARE motif of SNAP23
      cd15889
      Location:34 → 98
      SNARE_SNAP25N_23N; N-terminal SNARE motif of SNAP25 and SNAP23
      pfam00835
      Location:109 → 175
      SNAP-25; SNAP-25 family

    2. XM_005158727.4 → XP_005158784.1  synaptosome associated protein 23.1 isoform X2

      See identical proteins and their annotated locations for XP_005158784.1

      UniProtKB/TrEMBL
      A0A0R4IW20, A0A8N7XJG5, F6NZC2, Q7ZVE4
      Conserved Domains (3) summary
      cd15884
      Location:154 → 212
      SNARE_SNAP23C; C-terminal SNARE motif of SNAP23
      cd15889
      Location:11 → 75
      SNARE_SNAP25N_23N; N-terminal SNARE motif of SNAP25 and SNAP23
      pfam00835
      Location:86 → 152
      SNAP-25; SNAP-25 family
    Nucleotide Protein
    Heading Accession and Version

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