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    senp7b SUMO specific peptidase 7b [ Danio rerio (zebrafish) ]

    Gene ID: 100006377, updated on 9-Dec-2024

    Summary

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    Official Symbol
    senp7bprovided by ZNC
    Official Full Name
    SUMO specific peptidase 7bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060531-45
    See related
    Ensembl:ENSDARG00000061138 AllianceGenome:ZFIN:ZDB-GENE-060531-45
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    senp7; fc07g08; wu:fc07g08; si:dkey-21o6.1; si:ch211-239j15.4
    Summary
    Predicted to enable SUMO-specific endopeptidase activity. Predicted to be involved in protein desumoylation. Predicted to act upstream of or within proteolysis. Predicted to be active in cytoplasm and nucleus. Orthologous to human SENP7 (SUMO specific peptidase 7). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See senp7b in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (28236733..28308991)
    105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (28286586..28358870)

    Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488962 Neighboring gene uncharacterized LOC137488961 Neighboring gene interphotoreceptor matrix proteoglycan 2b Neighboring gene ABI family, member 3 (NESH) binding protein b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Integrative view of α2,3-sialyltransferases (ST3Gal) molecular and functional evolution in deuterostomes: significance of lineage-specific losses. Petit D, et al. Mol Biol Evol, 2015 Apr. PMID 25534026, Free PMC Article
    2. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables cysteine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    sentrin-specific protease 7b
    Names
    SUMO1/sentrin specific peptidase 7
    SUMO1/sentrin specific peptidase 7b
    NP_001116418.1
    XP_005161832.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001122946.1 → NP_001116418.1  sentrin-specific protease 7b

      Status: PROVISIONAL

      Source sequence(s)
      CR361552
      UniProtKB/TrEMBL
      A0A8M1NGG0, Q1L9B2
      Related
      ENSDARP00000081302.6, ENSDART00000086868.8
      Conserved Domains (1) summary
      cl23802
      Location:596 → 840
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007133.7 Reference GRCz11 Primary Assembly

      Range
      28236733..28308991
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005161775.5 → XP_005161832.1  sentrin-specific protease 7b isoform X1

      UniProtKB/TrEMBL
      A0A8M2B8Q7
      Conserved Domains (1) summary
      cl23802
      Location:601 → 845
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395115.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      93413..174413
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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