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    exoc6b exocyst complex component 6B [ Danio rerio (zebrafish) ]

    Gene ID: 767763, updated on 27-Dec-2024

    Summary

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    Official Symbol
    exoc6bprovided by ZNC
    Official Full Name
    exocyst complex component 6Bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060929-132
    See related
    Ensembl:ENSDARG00000098874 AllianceGenome:ZFIN:ZDB-GENE-060929-132
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fa55b02; wu:fa55b02; zgc:153610
    Summary
    Predicted to be involved in vesicle tethering involved in exocytosis. Predicted to act upstream of or within exocytosis and intracellular protein transport. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia with joint laxity type 3. Orthologous to human EXOC6B (exocyst complex component 6B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See exoc6b in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (25135739..25294036)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (24864582..25022879)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene zgc:101765 Neighboring gene membrane anchored junction protein Neighboring gene BCL2 associated agonist of cell death b Neighboring gene cytochrome P450, family 26, subfamily b, polypeptide 1 Neighboring gene dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive) Neighboring gene uncharacterized LOC137496166

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Retinoic acid metabolic genes, meiosis, and gonadal sex differentiation in zebrafish. Rodríguez-Marí A, et al. PLoS One, 2013. PMID 24040125, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC153610

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within vesicle tethering involved in exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle tethering involved in exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    exocyst complex component 6B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076730.3 → NP_001070198.3  exocyst complex component 6B

      Status: VALIDATED

      Source sequence(s)
      AL954715, CT030133, CU464085
      UniProtKB/TrEMBL
      A0A0R4ILM6, A0A8M1NB43, A0A8M3AU30
      Related
      ENSDARP00000134880.1, ENSDART00000167326.3
      Conserved Domains (1) summary
      pfam04091
      Location:456 → 762
      Sec15; Exocyst complex subunit Sec15-like

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      25135739..25294036
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021477610.2 → XP_021333285.1  exocyst complex component 6B isoform X1

      UniProtKB/TrEMBL
      A0A8M9Q814, A0A8M9QH78
      Conserved Domains (1) summary
      pfam04091
      Location:456 → 772
      Sec15; Exocyst complex subunit Sec15-like

    2. XM_068222411.1 → XP_068078512.1  exocyst complex component 6B isoform X2

      UniProtKB/TrEMBL
      A0A8M9Q814

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394690.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      105943..253829
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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