chchd4a coiled-coil-helix-coiled-coil-helix domain containing 4a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: chchd4aprovided by ZNC
Official Full Name: coiled-coil-helix-coiled-coil-helix domain containing 4aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040801-46
See related: Ensembl:ENSDARG00000033376 AllianceGenome:ZFIN:ZDB-GENE-040801-46
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: chchd4; fc10g04; wu:fc10g04; zgc:100849; si:dkey-202e22.1
Summary: Predicted to enable protein-disulfide reductase activity. Predicted to be involved in mitochondrial respiratory chain complex assembly; protein folding; and protein import into mitochondrial intermembrane space. Predicted to act upstream of or within protein transport. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial intermembrane space. Is expressed in brain; eye; head; liver; and somite. Orthologous to human CHCHD4 (coiled-coil-helix-coiled-coil-helix domain containing 4). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 11

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (34779606..34783938, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (34517613..34521945, complement)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables protein-disulfide reductase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein-disulfide reductase activity	IEA Inferred from Electronic Annotation more info
enables protein-disulfide reductase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in 'de novo' post-translational protein folding	ISS Inferred from Sequence or Structural Similarity more info
involved_in mitochondrial respiratory chain complex assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein import into mitochondrial intermembrane space	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein import into mitochondrial intermembrane space	IEA Inferred from Electronic Annotation more info
involved_in protein import into mitochondrial intermembrane space	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein maturation by protein folding	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein maturation by protein folding	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrial intermembrane space	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial intermembrane space	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: mitochondrial intermembrane space import and assembly protein 40

Names: coiled-coil-helix-coiled-coil-helix domain containing 4; coiled-coil-helix-coiled-coil-helix domain-containing protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.