sema3bl sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: sema3blprovided by ZNC
Official Full Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3blprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-2956
See related: Ensembl:ENSDARG00000007560 AllianceGenome:ZFIN:ZDB-GENE-030131-2956
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fc22d04; wu:fc22d04; si:ch211-106g4.1
Summary: Enables neuropilin binding activity. Predicted to be involved in several processes, including axon guidance; neural crest cell migration; and semaphorin-plexin signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human SEMA3G (semaphorin 3G). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	8	NC_007119.7 (26522013..26573963)
105	previous assembly	GRCz10 (GCF_000002035.5)	8	NC_007119.6 (26502874..26554824)

Chromosome 8 - NC_007119.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables chemorepellent activity	IBA Inferred from Biological aspect of Ancestor more info
enables neuropilin binding	IBA Inferred from Biological aspect of Ancestor more info
enables neuropilin binding	IDA Inferred from Direct Assay more info	PubMed
enables semaphorin receptor binding	IBA Inferred from Biological aspect of Ancestor more info
enables semaphorin receptor binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in axon guidance	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative chemotaxis	IBA Inferred from Biological aspect of Ancestor more info
involved_in neural crest cell migration	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of cell migration	IBA Inferred from Biological aspect of Ancestor more info
involved_in semaphorin-plexin signaling pathway	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl

Names: sema3g; semaphorin sem2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001122712.1 → NP_001116184.1 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl precursor

Status: PROVISIONAL

Source sequence(s)

BX548158

UniProtKB/TrEMBL

A0A8N1Z0Q5, M9MM97

Related

ENSDARP00000046862.7, ENSDART00000046863.9

Conserved Domains (4) summary

cd05871
Location:579 → 664

Ig_Semaphorin_classIII; Immunoglobulin (Ig)-like domain of class III semaphorin

cd11255
Location:42 → 515

Sema_3G; The Sema domain, a protein interacting module, of semaphorin 3G (Sema3G)

smart00410
Location:581 → 663

IG_like; Immunoglobulin like

smart00423
Location:514 → 550

PSI; domain found in Plexins, Semaphorins and Integrins