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    arf4b ADP-ribosylation factor 4b [ Danio rerio (zebrafish) ]

    Gene ID: 550402, updated on 27-Dec-2024

    Summary

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    Official Symbol
    arf4bprovided by ZNC
    Official Full Name
    ADP-ribosylation factor 4bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050417-205
    See related
    Ensembl:ENSDARG00000100339 AllianceGenome:ZFIN:ZDB-GENE-050417-205
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    arf4; zgc:112199
    Summary
    Predicted to enable GTP binding activity. Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Predicted to act upstream of or within protein transport. Predicted to be located in Golgi apparatus. Predicted to be active in cytoplasm and plasma membrane. Is expressed in brain; eye; forebrain; and midbrain. Orthologous to human ARF4 (ARF GTPase 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See arf4b in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (42466577..42472501, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) Unplaced Scaffold NW_003336639.1 (22141..23751, complement)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene sarcolemma associated protein a Neighboring gene uncharacterized LOC137496736 Neighboring gene DENN/MADD domain containing 6Aa Neighboring gene si:ch1073-165f9.2 Neighboring gene zgc:110286

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Proteomics profiling of single organs from individual adult zebrafish. Abramsson A, et al. Zebrafish, 2010 Jun. PMID 20392139
    2. Zebrafish fat-free, a novel Arf effector, regulates phospholipase D to mediate lipid and glucose metabolism. Liu HY, et al. Biochim Biophys Acta, 2010 Dec. PMID 20816853
    3. Rgp1 contributes to craniofacial cartilage development and Rab8a-mediated collagen II secretion. Ritter DJ, et al. Front Endocrinol (Lausanne), 2023. PMID 36843607, Free PMC Article
    4. Generation and characterization of a novel gne Knockout Model in Zebrafish. Livne H, et al. Front Cell Dev Biol, 2022. PMID 36353515, Free PMC Article
    5. Examining the responses of the zebrafish (Danio rerio) gastrointestinal system to the suspected obesogen diethylhexyl phthalate. Buerger AN, et al. Environ Pollut, 2019 Feb. PMID 30682743

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ADP-ribosylation factor 4b
    Names
    ADP-ribosylation factor 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017707.1 → NP_001017707.1  ADP-ribosylation factor 4b

      See identical proteins and their annotated locations for NP_001017707.1

      Status: PROVISIONAL

      Source sequence(s)
      BC093261
      UniProtKB/TrEMBL
      Q566Z9
      Related
      ENSDARP00000130845.2, ENSDART00000166624.2
      Conserved Domains (2) summary
      smart00178
      Location:15 → 174
      SAR; Sar1p-like members of the Ras-family of small GTPases
      cl21455
      Location:1 → 180
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      42466577..42472501 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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