pip4k2ab phosphatidylinositol-5-phosphate 4-kinase, type II, alpha b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: pip4k2abprovided by ZNC
Official Full Name: phosphatidylinositol-5-phosphate 4-kinase, type II, alpha bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-070912-272
See related: Ensembl:ENSDARG00000063544 AllianceGenome:ZFIN:ZDB-GENE-070912-272
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:ch211-279l9.5
Summary: Predicted to enable 1-phosphatidylinositol-5-phosphate 4-kinase activity and ATP binding activity. Predicted to act upstream of or within phosphatidylinositol metabolic process and phosphorylation. Predicted to be located in lysosome; nucleus; and plasma membrane. Orthologous to human PIP4K2A (phosphatidylinositol-5-phosphate 4-kinase type 2 alpha). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 2

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	2	NC_007113.7 (21089652..21157069)
105	previous assembly	GRCz10 (GCF_000002035.5)	2	NC_007113.6 (21431439..21499054)

Chromosome 2 - NC_007113.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 1-phosphatidylinositol-5-phosphate 4-kinase activity	IEA Inferred from Electronic Annotation more info
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables phosphatidylinositol kinase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within phosphatidylinositol metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in lysosome	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: phosphatidylinositol 5-phosphate 4-kinase type-2 alpha; phosphatidylinositol 5-phosphate 4-kinase type-2 beta

Names: phosphatidylinositol-5-phosphate 4-kinase, type II, beta

XP_005163424.1

EC 2.7.1.149

XP_683672.2

EC 2.7.1.149

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007113.7 Reference GRCz11 Primary Assembly

Range

21089652..21157069

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005163367.5 → XP_005163424.1 phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1

UniProtKB/TrEMBL

A0A8M2BAK4

Conserved Domains (1) summary

smart00330
Location:66 → 444

PIPKc; Phosphatidylinositol phosphate kinases
XM_678580.9 → XP_683672.2 phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X2

UniProtKB/TrEMBL

A0A8N7UUX6, B0UXW0

Related

ENSDARP00000113001.1, ENSDART00000139633.4

Conserved Domains (1) summary

smart00330
Location:66 → 412

PIPKc; Phosphatidylinositol phosphate kinases