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    spata13 spermatogenesis associated 13 [ Danio rerio (zebrafish) ]

    Gene ID: 568426, updated on 9-Dec-2024

    Summary

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    Official Symbol
    spata13provided by ZNC
    Official Full Name
    spermatogenesis associated 13provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-091116-25
    See related
    Ensembl:ENSDARG00000062837 AllianceGenome:ZFIN:ZDB-GENE-091116-25
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkey-33c18.3
    Summary
    Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in filopodium assembly and lamellipodium assembly. Predicted to be active in cytosol. Orthologous to human SPATA13 (spermatogenesis associated 13). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See spata13 in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (21864728..21903440, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (21719554..21758305, complement)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene suppressor of tumorigenicity 14 protein Neighboring gene transmembrane serine protease 7 Neighboring gene C1q and TNF related 9 Neighboring gene transgelin 3b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Duplication and subfunctionalisation of the general transcription factor IIIA (gtf3a) gene in teleost genomes, with ovarian specific transcription of gtf3ab. Rojo-Bartolomé I, et al. PLoS One, 2020. PMID 31999691, Free PMC Article
    2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in filopodium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in lamellipodium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    spermatogenesis-associated protein 13

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      21864728..21903440 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005162741.5 → XP_005162798.1  spermatogenesis-associated protein 13 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B9P0, E7F6C5
      Related
      ENSDARP00000085685.5, ENSDART00000091252.6
      Conserved Domains (3) summary
      smart00325
      Location:841 → 1020
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      cd01224
      Location:1025 → 1163
      PH_Collybistin_ASEF; Collybistin/APC-stimulated guanine nucleotide exchange factor pleckstrin homology (PH) domain
      cl17036
      Location:747 → 800
      SH3; Src Homology 3 domain superfamily

    2. XM_691753.10 → XP_696845.4  spermatogenesis-associated protein 13 isoform X2

      UniProtKB/TrEMBL
      A0A8M9PX66
      Conserved Domains (3) summary
      smart00325
      Location:813 → 992
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      cd01224
      Location:997 → 1135
      PH_Collybistin_ASEF; Collybistin/APC-stimulated guanine nucleotide exchange factor pleckstrin homology (PH) domain
      cl17036
      Location:719 → 772
      SH3; Src Homology 3 domain superfamily

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395172.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      55908..94624 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021473778.2 → XP_021329453.1  spermatogenesis-associated protein 13 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B9P0, E7F6C5
      Conserved Domains (3) summary
      smart00325
      Location:841 → 1020
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      cd01224
      Location:1025 → 1163
      PH_Collybistin_ASEF; Collybistin/APC-stimulated guanine nucleotide exchange factor pleckstrin homology (PH) domain
      cl17036
      Location:747 → 800
      SH3; Src Homology 3 domain superfamily

    2. XM_021473779.2 → XP_021329454.1  spermatogenesis-associated protein 13 isoform X2

      UniProtKB/TrEMBL
      A0A8M9PX66
      Conserved Domains (3) summary
      smart00325
      Location:813 → 992
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      cd01224
      Location:997 → 1135
      PH_Collybistin_ASEF; Collybistin/APC-stimulated guanine nucleotide exchange factor pleckstrin homology (PH) domain
      cl17036
      Location:719 → 772
      SH3; Src Homology 3 domain superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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