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    mtus1b microtubule associated tumor suppressor 1b [ Danio rerio (zebrafish) ]

    Gene ID: 557250, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mtus1bprovided by ZNC
    Official Full Name
    microtubule associated tumor suppressor 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070619-5
    See related
    AllianceGenome:ZFIN:ZDB-GENE-070619-5
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    mtus1
    Summary
    Predicted to be located in nucleus. Orthologous to human MTUS1 (microtubule associated scaffold protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See mtus1b in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (16520023..16617739)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (15827087..15924806)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110439786 Neighboring gene myotubularin related protein 7b Neighboring gene pericentriolar material 1 Neighboring gene N-acylsphingosine amidohydrolase (acid ceramidase) 1b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution of hes gene family in vertebrates: the hes5 cluster genes have specifically increased in frogs. Kuretani A, et al. BMC Ecol Evol, 2021 Jul 29. PMID 34325655, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    microtubule-associated tumor suppressor 1 homolog
    Names
    microtubule associated tumor suppressor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      16520023..16617739
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001919934.8 → XP_001919969.4  microtubule-associated tumor suppressor 1 homolog

      UniProtKB/TrEMBL
      A0A8M6Z0F8
      Conserved Domains (2) summary
      pfam05276
      Location:1099 → 1342
      SH3BP5; SH3 domain-binding protein 5 (SH3BP5)
      pfam09755
      Location:1109 → 1358
      DUF2046; Uncharacterized conserved protein H4 (DUF2046)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394468.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      168186..255113
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021471156.2 → XP_021326831.1  microtubule-associated tumor suppressor 1 homolog

      UniProtKB/TrEMBL
      A0A8M9PX35
      Conserved Domains (2) summary
      pfam07964
      Location:339 → 605
      Red1; Rec10 / Red1
      cl25732
      Location:1091 → 1356
      SMC_N; RecF/RecN/SMC N terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version

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