fdx1 ferredoxin 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: fdx1provided by ZNC
Official Full Name: ferredoxin 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-071015-2
See related: Ensembl:ENSDARG00000056410 AllianceGenome:ZFIN:ZDB-GENE-071015-2
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: im:6907289
Summary: Predicted to enable electron transfer activity. Acts upstream of or within negative regulation of epiboly involved in gastrulation with mouth forming second. Predicted to be active in mitochondrion. Is expressed in brain; digestive system; heart; and pleuroperitoneal region. Orthologous to human FDX1 (ferredoxin 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	9	NC_007120.7 (29520786..29527021)
105	previous assembly	GRCz10 (GCF_000002035.5)	9	NC_007120.6 (29709955..29716275)

Chromosome 9 - NC_007120.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Larvae with genetic disruption of fdx1b were morphologically inconspicuous.
Title: Ferredoxin 1b (Fdx1b) Is the Essential Mitochondrial Redox Partner for Cortisol Biosynthesis in Zebrafish.

Submit: New GeneRIF Correction

General gene information

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Markers

fk54b10.x1 (e-PCR)
- UniSTS:201156

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 2 iron, 2 sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables electron transfer activity	IBA Inferred from Biological aspect of Ancestor more info
enables iron-sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within P450-containing electron transport chain	IEA Inferred from Electronic Annotation more info
involved_in electron transport chain	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within negative regulation of epiboly involved in gastrulation with mouth forming second	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: adrenodoxin, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007120.7 Reference GRCz11 Primary Assembly

Range

29520786..29527021

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021478966.2 → XP_021334641.1 adrenodoxin, mitochondrial

UniProtKB/TrEMBL

A0A8M1QKT2, E7F7J1

Related

ENSDARP00000113657.1, ENSDART00000144430.3

Conserved Domains (1) summary

PLN02593
Location:53 → 155

PLN02593; adrenodoxin-like ferredoxin protein

Reference GRCz11 ALT_DRER_TU_1

Genomic

NW_018394759.1 Reference GRCz11 ALT_DRER_TU_1

Range

125901..132136

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_001922687.5 → XP_001922722.2 adrenodoxin, mitochondrial

UniProtKB/TrEMBL

A0A8M1QKT2, E7F7J1

Conserved Domains (1) summary

PLN02593
Location:53 → 155

PLN02593; adrenodoxin-like ferredoxin protein