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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001327987.1 → NP_001314916.1 testican-3 isoform a precursor
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a),
- Source sequence(s)
-
CR381587, EB939186, EH433753, EH447295, EH458122, EH468737
- UniProtKB/TrEMBL
- A0A0R4IMY5, A0A8M1P8M2, A0A8M3BEW5
- Related
- ENSDARP00000135664.2, ENSDART00000166479.2
- Conserved Domains (4) summary
-
- smart00280
Location:106 → 149
- KAZAL; Kazal type serine protease inhibitors
- cd00191
Location:275 → 339
- TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
- cd00252
Location:161 → 277
- SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
- pfam10591
Location:160 → 265
- SPARC_Ca_bdg; Secreted protein acidic and rich in cysteine Ca binding region
-
NM_001327988.1 → NP_001314917.1 testican-3 isoform b precursor
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in an isoform (b) that is shorter than isoform a.
- Source sequence(s)
-
CR381587, EB939186, EH433753, EH447295, EH458122, EH468737
- UniProtKB/TrEMBL
- A0A8M1P451, A0A8M3BEW5, F1RAX3
- Related
- ENSDARP00000123781.1, ENSDART00000148518.3
- Conserved Domains (4) summary
-
- smart00280
Location:103 → 146
- KAZAL; Kazal type serine protease inhibitors
- cd00191
Location:272 → 336
- TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
- cd00252
Location:158 → 274
- SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
- pfam10591
Location:157 → 262
- SPARC_Ca_bdg; Secreted protein acidic and rich in cysteine Ca binding region