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    glb1l galactosidase, beta 1-like [ Danio rerio (zebrafish) ]

    Gene ID: 100001628, updated on 9-Dec-2024

    Summary

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    Official Symbol
    glb1lprovided by ZNC
    Official Full Name
    galactosidase, beta 1-likeprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050309-196
    See related
    Ensembl:ENSDARG00000029955 AllianceGenome:ZFIN:ZDB-GENE-050309-196
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:7151535; wu:fj54e10; si:ch211-167j6.1
    Summary
    Predicted to enable beta-galactosidase activity. Predicted to be involved in galactose catabolic process. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be active in vacuole. Orthologous to human GLB1L (galactosidase beta 1 like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See glb1l in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (12847154..12866694)
    105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (12875951..12895491)

    Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene PTTG1 interacting protein b Neighboring gene myosin X, like 3 Neighboring gene si:ch211-167j6.3 Neighboring gene ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution of teleostean hatching enzyme genes and their paralogous genes. Kawaguchi M, et al. Dev Genes Evol, 2006 Dec. PMID 17016731
    2. Gene expression profiling of zebrafish embryonic retinal pigment epithelium in vivo. Leung YF, et al. Invest Ophthalmol Vis Sci, 2007 Feb. PMID 17251491, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables beta-galactosidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables beta-galactosidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity, acting on glycosyl bonds IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity, hydrolyzing O-glycosyl compounds IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in anatomical structure morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in galactose catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in vacuole IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    beta-galactosidase-1-like protein
    NP_001116328.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001122856.1 → NP_001116328.1  beta-galactosidase-1-like protein precursor

      Status: PROVISIONAL

      Source sequence(s)
      CR752651
      UniProtKB/TrEMBL
      A0A8M1NIB2, F1QXE8
      Related
      ENSDARP00000047190.5, ENSDART00000047191.6
      Conserved Domains (2) summary
      pfam01301
      Location:36 → 352
      Glyco_hydro_35; Glycosyl hydrolases family 35
      pfam13364
      Location:536 → 603
      BetaGal_dom4_5; Beta-galactosidase jelly roll domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007120.7 Reference GRCz11 Primary Assembly

      Range
      12847154..12866694
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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