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    bzw2 basic leucine zipper and W2 domains 2 [ Danio rerio (zebrafish) ]

    Gene ID: 393892, updated on 9-Dec-2024

    Summary

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    Official Symbol
    bzw2provided by ZNC
    Official Full Name
    basic leucine zipper and W2 domains 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-746
    See related
    Ensembl:ENSDARG00000035918 AllianceGenome:ZFIN:ZDB-GENE-040426-746
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    sb:eu935; zgc:55580
    Summary
    Predicted to be involved in regulation of translational initiation. Predicted to act upstream of or within regulation of translation. Predicted to be active in cytoplasm. Is expressed in myotome. Orthologous to human BZW2 (basic leucine zipper and W2 domains 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See bzw2 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (31009696..31042597, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (31422383..31455317, complement)

    Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene syncoilin, intermediate filament protein Neighboring gene retinoblastoma binding protein 4 Neighboring gene ankyrin repeat and MYND domain-containing protein 2-like Neighboring gene sclerostin domain containing 1b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic and evolutionary relationships and developmental expression patterns of the zebrafish twist gene family. Yeo GH, et al. Dev Genes Evol, 2009 Jun. PMID 19565261
    2. Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing. Zhang Y, et al. Cell Rep, 2017 Jan 10. PMID 28076796, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC55580

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of translational initiation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    eIF5-mimic protein 1
    Names
    DKEYP-25A3.4
    basic leucine zipper and W2 domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200918.1 → NP_957212.1  eIF5-mimic protein 1

      See identical proteins and their annotated locations for NP_957212.1

      Status: PROVISIONAL

      Source sequence(s)
      BC048052
      UniProtKB/Swiss-Prot
      Q1LUC1
      Related
      ENSDARP00000123337.1, ENSDART00000136213.3
      Conserved Domains (1) summary
      cd11560
      Location:220 → 410
      W2_eIF5C_like; C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007130.7 Reference GRCz11 Primary Assembly

      Range
      31009696..31042597 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005159605.4 → XP_005159662.1  eIF5-mimic protein 1 isoform X1

      See identical proteins and their annotated locations for XP_005159662.1

      UniProtKB/Swiss-Prot
      Q1LUC1, Q7ZUN5
      UniProtKB/TrEMBL
      A0A8M9PN66
      Related
      ENSDARP00000152624.1, ENSDART00000190949.1
      Conserved Domains (1) summary
      cd11560
      Location:220 → 410
      W2_eIF5C_like; C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins

    2. XM_068215051.1 → XP_068071152.1  eIF5-mimic protein 1 isoform X1

      UniProtKB/Swiss-Prot
      Q1LUC1, Q7ZUN5
      UniProtKB/TrEMBL
      A0A8M9PN66

    3. XM_068215050.1 → XP_068071151.1  eIF5-mimic protein 1 isoform X1

      UniProtKB/Swiss-Prot
      Q1LUC1, Q7ZUN5
      UniProtKB/TrEMBL
      A0A8M9PN66

    4. XM_068215049.1 → XP_068071150.1  eIF5-mimic protein 1 isoform X1

      UniProtKB/Swiss-Prot
      Q1LUC1, Q7ZUN5
      UniProtKB/TrEMBL
      A0A8M9PN66

    5. XM_005159606.2 → XP_005159663.1  eIF5-mimic protein 1 isoform X1

      See identical proteins and their annotated locations for XP_005159663.1

      UniProtKB/Swiss-Prot
      Q1LUC1, Q7ZUN5
      UniProtKB/TrEMBL
      A0A8M9PN66
      Conserved Domains (1) summary
      cd11560
      Location:220 → 410
      W2_eIF5C_like; C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q1LUC1.1 GenPept UniProtKB/Swiss-Prot:Q1LUC1

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