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    pggt1b protein geranylgeranyltransferase type I, beta subunit [ Danio rerio (zebrafish) ]

    Gene ID: 570808, updated on 9-Dec-2024

    Summary

    Official Symbol
    pggt1bprovided by ZNC
    Official Full Name
    protein geranylgeranyltransferase type I, beta subunitprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050913-85
    See related
    Ensembl:ENSDARG00000103464 AllianceGenome:ZFIN:ZDB-GENE-050913-85
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:114070
    Summary
    Predicted to enable protein geranylgeranyltransferase activity. Predicted to contribute to CAAX-protein geranylgeranyltransferase activity. Acts upstream of or within blood vessel maturation. Predicted to be part of CAAX-protein geranylgeranyltransferase complex. Orthologous to human PGGT1B (protein geranylgeranyltransferase type I subunit beta). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
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    Genomic context

    See pggt1b in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (411977..418998, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (411977..418998, complement)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene spermatogenesis associated serine rich 2 Neighboring gene tripartite motif containing 36 Neighboring gene si:ch211-87m7.1 Neighboring gene PYM homolog 1, exon junction complex associated factor Neighboring gene solute carrier family 12 member 2-like Neighboring gene fem-1 homolog c

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC114070

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    contributes_to CAAX-protein geranylgeranyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables CAAX-protein geranylgeranyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables prenyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein geranylgeranyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein prenyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within blood vessel maturation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within protein geranylgeranylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of CAAX-protein geranylgeranyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of CAAX-protein geranylgeranyltransferase complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    geranylgeranyl transferase type-1 subunit beta
    Names
    ggt1b
    NP_001025426.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001030255.2NP_001025426.1  geranylgeranyl transferase type-1 subunit beta

      See identical proteins and their annotated locations for NP_001025426.1

      Status: PROVISIONAL

      Source sequence(s)
      BC097132
      UniProtKB/TrEMBL
      Q4V8Z9
      Related
      ENSDARP00000136678.1, ENSDART00000166683.1
      Conserved Domains (2) summary
      COG5029
      Location:10331
      CAL1; Prenyltransferase, beta subunit [Posttranslational modification, protein turnover, chaperones, Lipid transport and metabolism]
      cd02895
      Location:11321
      GGTase-I; Geranylgeranyltransferase types I (GGTase-I)-like proteins containing the protein prenyltransferase (PTase) domain, beta subunit (alpha 6 - alpha 6 barrel fold). GGTase-I s are a subgroup of the protein prenyltransferase family of lipid-modifying enzymes ...

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      411977..418998 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)