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    bri3 brain protein I3 [ Danio rerio (zebrafish) ]

    Gene ID: 100002236, updated on 9-Dec-2024

    Summary

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    Official Symbol
    bri3provided by ZNC
    Official Full Name
    brain protein I3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-3038
    See related
    Ensembl:ENSDARG00000086332 AllianceGenome:ZFIN:ZDB-GENE-030131-3038
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc25e01; fc63g12; wu:fc25e01; wu:fc63g12
    Summary
    Predicted to be located in lysosomal membrane and perinuclear region of cytoplasm. Orthologous to human BRI3 (brain protein I3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See bri3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (61391580..61398936)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (61158992..61166348)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 721 Neighboring gene zinc finger protein 721-like Neighboring gene BAR/IMD domain containing adaptor protein 2 like 1b Neighboring gene zinc finger protein 91-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Reduced synaptic density and deficient locomotor response in neuronal activity-regulated pentraxin 2a mutant zebrafish. Elbaz I, et al. FASEB J, 2015 Apr. PMID 25466900
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in lysosomal membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    membrane protein BRI3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001200039.1 → NP_001186968.1  membrane protein BRI3

      Status: VALIDATED

      Source sequence(s)
      BC066460, CU464205
      UniProtKB/TrEMBL
      A0A8M1NWM0, E7FAC9
      Related
      ENSDARP00000108026.1, ENSDART00000126417.3
      Conserved Domains (1) summary
      pfam10164
      Location:13 → 129
      DUF2367; Uncharacterized conserved protein (DUF2367)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      61391580..61398936
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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