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    PDF2 prefoldin 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821819, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PDF2
    Official Full Name
    prefoldin 2
    Primary source
    TAIR:AT3G22480
    Locus tag
    AT3G22480
    See related
    Araport:AT3G22480
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    prefoldin 2
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    Genomic context

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    See PDF2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    2
    Sequence:
    Chromosome: 3; NC_003074.8 (7967989..7969705)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene FRIGIDA-like protein Neighboring gene Ribosomal L18p/L5e family protein Neighboring gene O-acetylserine (thiol) lyase (OAS-TL) isoform A2 Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene ncRNA Neighboring gene Seed maturation protein Neighboring gene miscRNA Neighboring gene Seed maturation protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The unconventional prefoldin RPB5 interactor mediates the gravitropic response by modulating cytoskeleton organization and auxin transport in Arabidopsis. Yang Y, et al. J Integr Plant Biol, 2022 Oct. PMID 35943836
    2. Prefoldin 6 is required for normal microtubule dynamics and organization in Arabidopsis. Gu Y, et al. Proc Natl Acad Sci U S A, 2008 Nov 18. PMID 19004800, Free PMC Article
    3. Prefoldins 3 and 5 play an essential role in Arabidopsis tolerance to salt stress. Rodríguez-Milla MA, et al. Mol Plant, 2009 May. PMID 19825635
    4. Prefoldins contribute to maintaining the levels of the spliceosome LSM2-8 complex through Hsp90 in Arabidopsis. Esteve-Bruna D, et al. Nucleic Acids Res, 2020 Jun 19. PMID 32396196, Free PMC Article
    5. Prefoldins Negatively Regulate Cold Acclimation in Arabidopsis thaliana by Promoting Nuclear Proteasome-Mediated HY5 Degradation. Perea-Resa C, et al. Mol Plant, 2017 Jun 5. PMID 28412546

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_113147.4
    NM_180295.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to gibberellin stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in cortical microtubule organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_positive_effect mRNA processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein folding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of prefoldin complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    prefoldin 2
    NP_188887.1
    • prefoldin 2 (PDF2); FUNCTIONS IN: unfolded protein binding; INVOLVED IN: protein folding; LOCATED IN: prefoldin complex; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Prefoldin beta-like (InterPro:IPR002777), Prefoldin (InterPro:IPR009053); Has 423 Blast hits to 423 proteins in 206 species: Archae - 15; Bacteria - 0; Metazoa - 139; Fungi - 122; Plants - 68; Viruses - 0; Other Eukaryotes - 79 (source: NCBI BLink).
    NP_850626.1
    • prefoldin 2 (PDF2); FUNCTIONS IN: unfolded protein binding; INVOLVED IN: protein folding; LOCATED IN: prefoldin complex; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Prefoldin beta-like (InterPro:IPR002777), Prefoldin (InterPro:IPR009053); Has 423 Blast hits to 423 proteins in 206 species: Archae - 15; Bacteria - 0; Metazoa - 139; Fungi - 122; Plants - 68; Viruses - 0; Other Eukaryotes - 79 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      7967989..7969705
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113147.4 → NP_188887.1  prefoldin 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188887.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LJ98
      UniProtKB/TrEMBL
      A0A178VHK8, A0A384K9E8, Q56X68
      Conserved Domains (1) summary
      pfam01920
      Location:20 → 121
      Prefoldin_2; Prefoldin subunit

    2. NM_180295.1 → NP_850626.1  prefoldin 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850626.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LJ98
      UniProtKB/TrEMBL
      A0A178VHK8, A0A384K9E8, Q56X68
      Conserved Domains (1) summary
      pfam01920
      Location:20 → 121
      Prefoldin_2; Prefoldin subunit
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LJ98.1

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