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    PMSR4 peptide met sulfoxide reductase 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828616, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PMSR4
    Official Full Name
    peptide met sulfoxide reductase 4
    Primary source
    TAIR:AT4G25130
    Locus tag
    AT4G25130
    See related
    Araport:AT4G25130
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F24A6.2; methionine sulfoxide reductase A4; MSRA4; peptide met sulfoxide reductase 4
    Summary
    Encodes a chloroplast-localized methionine sulfoxide reductase that is a member of the MSRA family. Involved in protection of chloroplasts from oxidative stress.
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    Genomic context

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    See PMSR4 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    2
    Sequence:
    Chromosome: 4; NC_003075.7 (12898514..12900090, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene metacaspase 2 Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene HAD superfamily, subfamily IIIB acid phosphatase Neighboring gene oleosin 1 Neighboring gene U-box domain-containing protein kinase family protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Investigations into the role of the plastidial peptide methionine sulfoxide reductase in response to oxidative stress in Arabidopsis. Romero HM, et al. Plant Physiol, 2004 Nov. PMID 15516509, Free PMC Article
    2. Differential regulation of plastidial and cytosolic isoforms of peptide methionine sulfoxide reductase in Arabidopsis. Sadanandom A, et al. Plant Physiol, 2000 May. PMID 10806242, Free PMC Article
    3. Plant methionine sulfoxide reductase A and B multigenic families. Rouhier N, et al. Photosynth Res, 2006 Sep. PMID 17031545
    4. Quantitative proteomics of a chloroplast SRP54 sorting mutant and its genetic interactions with CLPC1 in Arabidopsis. Rutschow H, et al. Plant Physiol, 2008 Sep. PMID 18633119, Free PMC Article
    5. AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins. Ferro M, et al. Mol Cell Proteomics, 2010 Jun. PMID 20061580, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_118645.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables peptide-methionine (S)-S-oxide reductase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to oxidative stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    NOT involved_in response to far red light TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in response to light stimulus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    NOT involved_in response to red light TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in chloroplast envelope HDA PubMed 
    located_in chloroplast stroma HDA PubMed 
    located_in chloroplast stroma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    peptide met sulfoxide reductase 4
    NP_194243.1
    • peptide met sulfoxide reductase 4 (PMSR4); FUNCTIONS IN: peptide-methionine-(S)-S-oxide reductase activity; INVOLVED IN: protein modification process, cellular response to oxidative stress; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Peptide methionine sulphoxide reductase MsrA (InterPro:IPR002569); BEST Arabidopsis thaliana protein match is: peptidemethionine sulfoxide reductase 1 (TAIR:AT5G61640.1); Has 10332 Blast hits to 10330 proteins in 2437 species: Archae - 129; Bacteria - 6211; Metazoa - 196; Fungi - 136; Plants - 235; Viruses - 1; Other Eukaryotes - 3424 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      12898514..12900090 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118645.4 → NP_194243.1  peptide met sulfoxide reductase 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194243.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P54150, Q8LAX4, Q94A72, Q9SW13
      UniProtKB/TrEMBL
      A0A178UYS9, A0A5S9XWK0
      Conserved Domains (1) summary
      pfam01625
      Location:96 → 236
      PMSR; Peptide methionine sulfoxide reductase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P54150.2

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