Sult2a6 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Sult2a6provided by RGD
Official Full Name: sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6provided by RGD
Primary source: RGD:3727
See related: EnsemblRapid:ENSRNOG00000047986 AllianceGenome:RGD:3727
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: ST-41; ST2A6; Smp2a; St2a2; BAST I; RATSMP2A; RATSMP2B; Sult2al1; Sult2a4l1
Summary: Predicted to enable sulfotransferase activity. Predicted to be involved in sulfation. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human SULT2A1 (sulfotransferase family 2A member 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward (RPKM 10922.3) See more
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Genomic context

Location:: 1q21

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (84046685..84097808, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (74911097..74962239, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (76529121..76722965, complement)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

RH94657 (e-PCR)
- UniSTS:119904

D1Wox13 (e-PCR)
- UniSTS:118118

RH139020 (e-PCR)
- UniSTS:221106

D1Got74 (e-PCR)
- UniSTS:113865

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables alcohol sulfotransferase activity	IEA Inferred from Electronic Annotation more info
enables bile-salt sulfotransferase activity	IEA Inferred from Electronic Annotation more info
enables sulfotransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables sulfotransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in steroid metabolic process	IEA Inferred from Electronic Annotation more info
involved_in sulfation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: sulfotransferase 2A6

Names: AD-ST; ST-40; STA; Sult2al1, sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 1; alcohol sulfotransferase A; androsterone-sulfating sulfotransferase; bile acid:3'phosphoadenosine-5'phosphosulfate:sulfotransferase I; hydroxysteroid sulfotransferase A; senescence marker protein 2A gene, exons 1 and 2; sulfotransferase 2A2; sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 4-like 1; sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 1

NP_036827.3

EC 2.8.2.14

EC 2.8.2.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.