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    Hspa12a heat shock protein family A (Hsp70) member 12A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 307997, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Hspa12aprovided by RGD
    Official Full Name
    heat shock protein family A (Hsp70) member 12Aprovided by RGD
    Primary source
    RGD:1305531
    See related
    EnsemblRapid:ENSRNOG00000018019 AllianceGenome:RGD:1305531
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Orthologous to human HSPA12A (heat shock protein family A (Hsp70) member 12A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 185.6), Kidney (RPKM 91.7) and 6 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Hspa12a in Genome Data Viewer
    Location:
    1q55
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (267921780..268083171, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (257935642..258096602, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (279946809..280104366, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene pancreatic lipase related protein 2 Neighboring gene sperm microtubule inner protein 5 Neighboring gene uncharacterized LOC134485263 Neighboring gene uncharacterized LOC134485262 Neighboring gene enolase 4 Neighboring gene shootin 1 Neighboring gene small nucleolar RNA SNORA48

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, et al. J Proteome Res, 2012 Sep 7. PMID 22871113, Free PMC Article
    2. Large-scale proteomics and phosphoproteomics of urinary exosomes. Gonzales PA, et al. J Am Soc Nephrol, 2009 Feb. PMID 19056867, Free PMC Article
    3. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    heat shock 70 kDa protein 12A
    Names
    heat shock 70kDa protein 12A
    heat shock protein 12A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107445.1 → NP_001100915.1  heat shock 70 kDa protein 12A

      See identical proteins and their annotated locations for NP_001100915.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473986
      UniProtKB/TrEMBL
      A0A8I6A9B3, A6JI70, D3ZC55
      Related
      ENSRNOP00000024548.4, ENSRNOT00000024548.7
      Conserved Domains (1) summary
      cd11735
      Location:57 → 523
      HSPA12A_like_NBD; Nucleotide-binding domain of HSPA12A and similar proteins

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      267921780..268083171 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063288266.1 → XP_063144336.1  heat shock 70 kDa protein 12A isoform X2

      UniProtKB/TrEMBL
      A0A8I6A9B3
      Related
      ENSRNOP00000090050.2, ENSRNOT00000100455.2

    2. XM_017589080.3 → XP_017444569.1  heat shock 70 kDa protein 12A isoform X1

      UniProtKB/TrEMBL
      A0A8I6A691, A0A8I6A9B3
      Related
      ENSRNOP00000086907.1, ENSRNOT00000109008.2

    3. XM_063288270.1 → XP_063144340.1  heat shock 70 kDa protein 12A isoform X3

      UniProtKB/TrEMBL
      A0A8I6A9B3
    Nucleotide Protein Strain
    Heading Accession and Version

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