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    Acbd6 acyl-CoA binding domain containing 6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 289125, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Acbd6provided by RGD
    Official Full Name
    acyl-CoA binding domain containing 6provided by RGD
    Primary source
    RGD:1305030
    See related
    EnsemblRapid:ENSRNOG00000003550 AllianceGenome:RGD:1305030
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable fatty-acyl-CoA binding activity. Predicted to be located in cytoplasm and nucleus. Orthologous to human ACBD6 (acyl-CoA binding domain containing 6). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 58.7), Brain (RPKM 48.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Acbd6 in Genome Data Viewer
    Location:
    13q21
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (70277036..70412598)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (67726786..67863392)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (73196504..73334077)

    Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102547468 Neighboring gene ribosomal protein S17 like 3 Neighboring gene deoxyuridine triphosphatase pseudogene Neighboring gene 60S ribosomal protein L37-like Neighboring gene LIM homeobox 4 Neighboring gene quiescin sulfhydryl oxidase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables fatty-acyl-CoA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables fatty-acyl-CoA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables fatty-acyl-CoA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables fatty-acyl-CoA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lipid binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables lipid binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    acyl-CoA-binding domain-containing protein 6
    Names
    acyl-Coenzyme A binding domain containing 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001011906.1 → NP_001011906.1  acyl-CoA-binding domain-containing protein 6

      See identical proteins and their annotated locations for NP_001011906.1

      Status: PROVISIONAL

      Source sequence(s)
      BC086598
      UniProtKB/Swiss-Prot
      Q5RJK8
      UniProtKB/TrEMBL
      A6ICY9
      Related
      ENSRNOP00000004772.5, ENSRNOT00000004772.8
      Conserved Domains (4) summary
      cd00204
      Location:165 → 261
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam00887
      Location:44 → 123
      ACBP; Acyl CoA binding protein
      pfam12796
      Location:166 → 255
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:191 → 222
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086031.1 Reference GRCr8

      Range
      70277036..70412598
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006250031.5 → XP_006250093.1  acyl-CoA-binding domain-containing protein 6 isoform X2

      Conserved Domains (4) summary
      cd00204
      Location:126 → 198
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam00887
      Location:44 → 123
      ACBP; Acyl CoA binding protein
      pfam12796
      Location:110 → 192
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:128 → 159
      ANK; ANK repeat [structural motif]

    2. XM_006250036.5 → XP_006250098.1  acyl-CoA-binding domain-containing protein 6 isoform X4

      UniProtKB/TrEMBL
      A0A8I6A4U8
      Related
      ENSRNOP00000085910.1, ENSRNOT00000109039.2
      Conserved Domains (1) summary
      pfam00887
      Location:44 → 123
      ACBP; Acyl CoA binding protein

    3. XM_039090468.2 → XP_038946396.1  acyl-CoA-binding domain-containing protein 6 isoform X1

      Conserved Domains (3) summary
      sd00045
      Location:194 → 225
      ANK; ANK repeat [structural motif]
      pfam00887
      Location:44 → 123
      ACBP; Acyl CoA binding protein
      pfam12796
      Location:168 → 225
      Ank_2; Ankyrin repeats (3 copies)

    4. XM_017598704.3 → XP_017454193.1  acyl-CoA-binding domain-containing protein 6 isoform X3

    RNA

    1. XR_010056910.1 RNA Sequence

    2. XR_595498.4 RNA Sequence

    3. XR_005492218.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5RJK8.1 GenPept UniProtKB/Swiss-Prot:Q5RJK8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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