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    B3galt1 Beta-1,3-galactosyltransferase 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 366064, updated on 9-Dec-2024

    Summary

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    Official Symbol
    B3galt1provided by RGD
    Official Full Name
    Beta-1,3-galactosyltransferase 1provided by RGD
    Primary source
    RGD:1311898
    See related
    EnsemblRapid:ENSRNOG00000007625 AllianceGenome:RGD:1311898
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity. Predicted to be involved in galactosylceramide biosynthetic process; lipid glycosylation; and protein O-linked glycosylation. Predicted to act upstream of or within oligosaccharide biosynthetic process. Predicted to be active in Golgi membrane. Orthologous to human B3GALT1 (beta-1,3-galactosyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 124.2), Brain (RPKM 30.5) and 1 other tissue See more
    Orthologs
    human mouse all
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    Genomic context

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    See B3galt1 in Genome Data Viewer
    Location:
    3q21
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (72661410..73234447)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (52253413..52826508)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (53699409..54269612)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA17 Neighboring gene uncharacterized LOC134486373 Neighboring gene xin actin-binding repeat containing 2 Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC134486374 Neighboring gene uncharacterized LOC100911723 Neighboring gene serine threonine kinase 39 Neighboring gene dnaJ homolog subfamily C member 8-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta-nacetyl-galactosamine beta-1,3-galactosyltransferase family. Amado M, et al. J Biol Chem, 1998 May 22. PMID 9582303
    2. Genomic cloning and expression of three murine UDP-galactose: beta-N-acetylglucosamine beta1,3-galactosyltransferase genes. Hennet T, et al. J Biol Chem, 1998 Jan 2. PMID 9417047
    3. Proteomics characterization of abundant Golgi membrane proteins. Bell AW, et al. J Biol Chem, 2001 Feb 16. PMID 11042173
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in galactosylceramide biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in lipid glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in lipid glycosylation ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within oligosaccharide biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in oligosaccharide biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein O-linked glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    beta-1,3-galactosyltransferase 1
    Names
    UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase 1
    UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
    NP_001102424.1
    XP_017447431.1
    XP_017447434.1
    XP_017447435.1
    XP_017447437.1
    XP_038961517.1
    XP_038961518.1
    XP_063140336.1
    XP_063140337.1
    XP_063140338.1
    XP_063140339.1
    XP_063140341.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108954.2 → NP_001102424.1  beta-1,3-galactosyltransferase 1

      See identical proteins and their annotated locations for NP_001102424.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A6HLY9, D3ZPD8
      Conserved Domains (1) summary
      pfam01762
      Location:92 → 279
      Galactosyl_T; Galactosyltransferase

    2. NM_001434404.1 → NP_001421333.1  beta-1,3-galactosyltransferase 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A6HLY9, D3ZPD8

    3. NM_001434405.1 → NP_001421334.1  beta-1,3-galactosyltransferase 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A6HLY9, D3ZPD8

    RNA

    1. NR_197780.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003

    2. NR_197781.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003

    3. NR_197782.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      72661410..73234447
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017591942.3 → XP_017447431.1  beta-1,3-galactosyltransferase 1 isoform X2

      UniProtKB/TrEMBL
      A6HLY9, D3ZPD8
      Related
      ENSRNOP00000010018.4, ENSRNOT00000010018.6
      Conserved Domains (1) summary
      pfam01762
      Location:92 → 279
      Galactosyl_T; Galactosyltransferase

    2. XM_039105589.2 → XP_038961517.1  beta-1,3-galactosyltransferase 1 isoform X2

      UniProtKB/TrEMBL
      A6HLY9, D3ZPD8
      Conserved Domains (1) summary
      pfam01762
      Location:92 → 279
      Galactosyl_T; Galactosyltransferase

    3. XM_017591945.3 → XP_017447434.1  beta-1,3-galactosyltransferase 1 isoform X2

      Related
      ENSRNOP00000106104.1, ENSRNOT00000138050.1
      Conserved Domains (1) summary
      pfam01762
      Location:92 → 279
      Galactosyl_T; Galactosyltransferase

    4. XM_063284271.1 → XP_063140341.1  beta-1,3-galactosyltransferase 1 isoform X2

      UniProtKB/TrEMBL
      A6HLY9, D3ZPD8
      Related
      ENSRNOP00000102829.1, ENSRNOT00000172616.1

    5. XM_063284269.1 → XP_063140339.1  beta-1,3-galactosyltransferase 1 isoform X1

    6. XM_063284268.1 → XP_063140338.1  beta-1,3-galactosyltransferase 1 isoform X1

    7. XM_063284266.1 → XP_063140336.1  beta-1,3-galactosyltransferase 1 isoform X1

    8. XM_063284267.1 → XP_063140337.1  beta-1,3-galactosyltransferase 1 isoform X1

    9. XM_017591946.3 → XP_017447435.1  beta-1,3-galactosyltransferase 1 isoform X2

      UniProtKB/TrEMBL
      A6HLY9, D3ZPD8
      Related
      ENSRNOP00000104470.1, ENSRNOT00000170985.1
      Conserved Domains (1) summary
      pfam01762
      Location:92 → 279
      Galactosyl_T; Galactosyltransferase

    10. XM_039105590.2 → XP_038961518.1  beta-1,3-galactosyltransferase 1 isoform X2

      UniProtKB/TrEMBL
      A6HLY9, D3ZPD8
      Conserved Domains (1) summary
      pfam01762
      Location:92 → 279
      Galactosyl_T; Galactosyltransferase

    11. XM_017591948.3 → XP_017447437.1  beta-1,3-galactosyltransferase 1 isoform X2

      Related
      ENSRNOP00000086959.1, ENSRNOT00000097712.2
      Conserved Domains (1) summary
      pfam01762
      Location:92 → 279
      Galactosyl_T; Galactosyltransferase
    Nucleotide Protein Strain
    Heading Accession and Version

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