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    4930522H14Rik RIKEN cDNA 4930522H14 gene [ Mus musculus (house mouse) ]

    Gene ID: 67646, updated on 9-Dec-2024

    Summary

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    Official Symbol
    4930522H14Rikprovided by MGI
    Official Full Name
    RIKEN cDNA 4930522H14 geneprovided by MGI
    Primary source
    MGI:MGI:1914896
    See related
    Ensembl:ENSMUSG00000060491 AllianceGenome:MGI:1914896
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700007J23Rik
    Summary
    Predicted to be located in membrane. Orthologous to human C1orf185 (chromosome 1 open reading frame 185). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis adult (RPKM 7.3) See more
    Orthologs
    human all
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    Genomic context

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    See 4930522H14Rik in Genome Data Viewer
    Location:
    4 C7; 4 51.29 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (109362529..109388494, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (109505332..109531297, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene tetratricopeptide repeat domain 39A Neighboring gene Ttc39a opposite strand RNA 1 Neighboring gene STARR-seq mESC enhancer starr_11070 Neighboring gene ring finger protein 11 Neighboring gene STARR-positive B cell enhancer ABC_E4645 Neighboring gene predicted gene, 22497 Neighboring gene predicted gene, 40226

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Combined Use of Whole Exome Sequencing and CRISPR/Cas9 to Study the Etiology of Non-Obstructive Azoospermia: Demonstration of the Dispensable Role of the Testis-Specific Genes C1orf185 and CCT6B. Cazin C, et al. Cells, 2021 Dec 30. PMID 35011680, Free PMC Article
    2. Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Miyata H, et al. Proc Natl Acad Sci U S A, 2016 Jul 12. PMID 27357688, Free PMC Article
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein C1orf185 homolog

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001199090.1 → NP_001186019.1  uncharacterized protein C1orf185 homolog isoform 2

      See identical proteins and their annotated locations for NP_001186019.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate exon in the 5' UTR and CDS, compared to variant 1. It encodes isoform 2, which has a shorter and distinct N-terminus, compared to variant 1.
      Source sequence(s)
      AK005726, AL627446
      Consensus CDS
      CCDS57290.1
      UniProtKB/Swiss-Prot
      Q9CPZ3
      Related
      ENSMUSP00000080923.8, ENSMUST00000082306.8
      Conserved Domains (1) summary
      pfam15842
      Location:3 → 186
      DUF4718; Domain of unknown function (DUF4718)

    2. NM_026291.3 → NP_080567.1  uncharacterized protein C1orf185 homolog isoform 1

      See identical proteins and their annotated locations for NP_080567.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the shorter transcript but encodes the longer isoform (1).
      Source sequence(s)
      AK019777, AL627446
      Consensus CDS
      CCDS18465.1
      UniProtKB/Swiss-Prot
      Q9CPZ3, Q9DAM0
      Related
      ENSMUSP00000099786.5, ENSMUST00000102725.11
      Conserved Domains (1) summary
      pfam15842
      Location:7 → 190
      DUF4718; Domain of unknown function (DUF4718)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      109362529..109388494 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CPZ3.1 GenPept UniProtKB/Swiss-Prot:Q9CPZ3

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