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    Disease resistance protein (TIR-NBS-LRR class) family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843617, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Disease resistance protein (TIR-NBS-LRR class) family
    Primary source
    TAIR:AT1G72860
    Locus tag
    AT1G72860
    See related
    Araport:AT1G72860
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F3N23.6; F3N23_6
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (27416228..27420946, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Disease resistance protein (TIR-NBS-LRR class) Neighboring gene Disease resistance protein (TIR-NBS class) Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Disease resistance protein (TIR-NBS class) Neighboring gene Survival protein SurE-like phosphatase/nucleotidase Neighboring gene Disease resistance protein (TIR-NBS class)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Truncated TIR-NBS Protein TN10 Pairs with Two Clustered TIR-NBS-LRR Immune Receptors and Contributes to Plant Immunity in Arabidopsis. Chen Y, et al. Int J Mol Sci, 2021 Apr 13. PMID 33924478, Free PMC Article
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001334556.1
    NM_001334557.1
    NM_105944.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ADP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of plant-type hypersensitive response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Disease resistance protein (TIR-NBS-LRR class) family
    NP_177429.2
    • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, ATP binding; INVOLVED IN: signal transduction, apoptosis, defense response, innate immune response; LOCATED IN: intrinsic to membrane; EXPRESSED IN: stem, leaf; CONTAINS InterPro DOMAIN/s: NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Disease resistance protein (InterPro:IPR000767), Toll-Interleukin receptor (InterPro:IPR000157); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT1G17600.1); Has 17128 Blast hits to 12682 proteins in 562 species: Archae - 4; Bacteria - 839; Metazoa - 1175; Fungi - 47; Plants - 14820; Viruses - 0; Other Eukaryotes - 243 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      27416228..27420946 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105944.2 → NP_177429.2  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177429.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WJ87, F4IF00, Q9SSP0
      Conserved Domains (4) summary
      PLN03210
      Location:1 → 721
      PLN03210; Resistant to P. syringae 6; Provisional
      COG4886
      Location:891 → 1143
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:918 → 940
      LRR_RI; leucine-rich repeat [structural motif]
      pfam01582
      Location:12 → 176
      TIR; TIR domain

    2. NM_001334556.1 → NP_001322142.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AT27, Q9SSP0
      Conserved Domains (2) summary
      PLN03210
      Location:1 → 1262
      PLN03210; Resistant to P. syringae 6; Provisional
      sd00033
      Location:887 → 909
      LRR_RI; leucine-rich repeat [structural motif]

    3. NM_001334557.1 → NP_001322143.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WHF0, A0A1P8AT23, A0A384LML1, Q9SSP0
    Nucleotide Protein
    Heading Accession and Version

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