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    Hsbp1l1 heat shock factor binding protein 1-like 1 [ Mus musculus (house mouse) ]

    Gene ID: 66255, updated on 9-Dec-2024

    Summary

    Official Symbol
    Hsbp1l1provided by MGI
    Official Full Name
    heat shock factor binding protein 1-like 1provided by MGI
    Primary source
    MGI:MGI:1913505
    See related
    Ensembl:ENSMUSG00000078963 AllianceGenome:MGI:1913505
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1810005K13Rik
    Summary
    Predicted to enable transcription corepressor activity. Predicted to be involved in cellular heat acclimation. Predicted to be active in cytosol and nucleus. Orthologous to human HSBP1L1 (heat shock factor binding protein 1 like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in testis adult (RPKM 1.4), kidney adult (RPKM 0.6) and 18 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Hsbp1l1 in Genome Data Viewer
    Location:
    18 E3; 18 53.35 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (80272154..80293329, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (80228939..80250102, complement)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E5666 Neighboring gene ribosome binding factor A, opposite strand Neighboring gene ribosome binding factor A Neighboring gene thioredoxin-like 4A Neighboring gene N(alpha)-acetyltransferase 12, NatA catalytic subunit Neighboring gene STARR-seq mESC enhancer starr_45175 Neighboring gene solute carrier family 66 member 2 Neighboring gene potassium voltage-gated channel, subfamily G, member 2 Neighboring gene predicted gene, 26676

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cellular heat acclimation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    heat shock factor-binding protein 1-like protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001136181.1NP_001129653.1  heat shock factor-binding protein 1-like protein 1

      See identical proteins and their annotated locations for NP_001129653.1

      Status: VALIDATED

      Source sequence(s)
      AC131065, AK141935, BC151118
      Consensus CDS
      CCDS50333.1
      UniProtKB/Swiss-Prot
      B2RXB2
      Related
      ENSMUSP00000132852.2, ENSMUST00000166219.2
      Conserved Domains (1) summary
      pfam06825
      Location:1462
      HSBP1; Heat shock factor binding protein 1

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      80272154..80293329 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006526518.5XP_006526581.1  heat shock factor-binding protein 1-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006526581.1

      UniProtKB/Swiss-Prot
      B2RXB2
      Conserved Domains (1) summary
      pfam06825
      Location:1462
      HSBP1; Heat shock factor binding protein 1
    2. XM_006526517.5XP_006526580.1  heat shock factor-binding protein 1-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006526580.1

      UniProtKB/Swiss-Prot
      B2RXB2
      Related
      ENSMUSP00000158095.2, ENSMUST00000237192.2
      Conserved Domains (1) summary
      pfam06825
      Location:1462
      HSBP1; Heat shock factor binding protein 1