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    UKL4 uridine kinase-like 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828757, updated on 18-Sep-2024

    Summary

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    Official Symbol
    UKL4
    Official Full Name
    uridine kinase-like 4
    Primary source
    TAIR:AT4G26510
    Locus tag
    AT4G26510
    See related
    Araport:AT4G26510
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    M3E9.60; M3E9_60; uridine kinase-like 4
    Summary
    One of the homologous genes predicted to encode proteins with UPRT domains (Uracil phosphoribosyltransferase). Five of these genes (At5g40870, At3g27190, At1g55810, At4g26510 and At3g27440) show a high level of identity, and are annotated as also containing a N-terminal uracil kinase (UK) domain. These genes are referred to as UKL1 (UK-like 1), UKL2, UKL3, UKL4 and UKL5, respectively.
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    Genomic context

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    See UKL4 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    16
    Sequence:
    Chromosome: 4; NC_003075.7 (13381687..13388362)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene methyltransferase small domain protein Neighboring gene ncRNA Neighboring gene Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family Neighboring gene chloroplast sulfur E Neighboring gene Aldolase superfamily protein Neighboring gene Aldolase superfamily protein Neighboring gene Leucine-rich repeat receptor-like protein kinase family protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    NM_001341804.1
    NM_001341805.1
    NM_118784.6
    NM_179117.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables uracil phosphoribosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables uridine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in CTP salvage IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in UMP salvage IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uridine kinase-like 4
    NP_001320072.1
    • uridine kinase-like 4 (UKL4); FUNCTIONS IN: uracil phosphoribosyltransferase activity, phosphotransferase activity, alcohol group as acceptor, kinase activity, ATP binding; INVOLVED IN: biosynthetic process, metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Phosphoribulokinase/uridine kinase (InterPro:IPR006083), Uridine kinase (InterPro:IPR000764); BEST Arabidopsis thaliana protein match is: uridine kinase-like 3 (TAIR:AT1G55810.3); Has 12683 Blast hits to 12669 proteins in 2628 species: Archae - 216; Bacteria - 9646; Metazoa - 520; Fungi - 504; Plants - 574; Viruses - 2; Other Eukaryotes - 1221 (source: NCBI BLink).
    NP_567747.4
    • uridine kinase-like 4 (UKL4); FUNCTIONS IN: uracil phosphoribosyltransferase activity, phosphotransferase activity, alcohol group as acceptor, kinase activity, ATP binding; INVOLVED IN: biosynthetic process, metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Phosphoribulokinase/uridine kinase (InterPro:IPR006083), Uridine kinase (InterPro:IPR000764); BEST Arabidopsis thaliana protein match is: uridine kinase-like 3 (TAIR:AT1G55810.3); Has 12621 Blast hits to 12607 proteins in 2610 species: Archae - 215; Bacteria - 9586; Metazoa - 520; Fungi - 503; Plants - 574; Viruses - 2; Other Eukaryotes - 1221 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      13381687..13388362
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001341804.1 → NP_001320072.1  uridine kinase-like 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O65583, Q0WQS9, Q8LD95, Q9SYU2
      UniProtKB/TrEMBL
      A0A178UWP6, A0A5S9XW28
      Conserved Domains (2) summary
      cd02023
      Location:51 → 244
      UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...
      pfam14681
      Location:265 → 466
      UPRTase; Uracil phosphoribosyltransferase

    2. NM_001341805.1 → NP_001328772.1  uridine kinase-like 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O65583, Q0WQS9, Q8LD95, Q9SYU2
      UniProtKB/TrEMBL
      A0A178UWP6, A0A5S9XW28
      Conserved Domains (2) summary
      cd02023
      Location:51 → 244
      UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...
      pfam14681
      Location:265 → 466
      UPRTase; Uracil phosphoribosyltransferase

    3. NM_118784.6 → NP_567747.4  uridine kinase-like 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567747.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O65583, Q0WQS9, Q8LD95, Q9SYU2
      UniProtKB/TrEMBL
      A0A178UWP6, A0A5S9XW28
      Conserved Domains (2) summary
      cd02023
      Location:51 → 244
      UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...
      pfam14681
      Location:265 → 466
      UPRTase; Uracil phosphoribosyltransferase

    4. NM_179117.5 → NP_849448.4  uridine kinase-like 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849448.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O65583, Q0WQS9, Q8LD95, Q9SYU2
      UniProtKB/TrEMBL
      A0A178UWP6, A0A5S9XW28
      Conserved Domains (2) summary
      cd02023
      Location:51 → 244
      UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...
      pfam14681
      Location:265 → 466
      UPRTase; Uracil phosphoribosyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O65583.2

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