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    NRPB11 DNA-directed RNA polymerase, RBP11-like protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824372, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NRPB11
    Official Full Name
    DNA-directed RNA polymerase, RBP11-like protein
    Primary source
    TAIR:AT3G52090
    Locus tag
    AT3G52090
    See related
    Araport:AT3G52090
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATRPB13.6; NRPD11; NRPE11; RNA POLYMERASE II 13.6 KDA SUBUNIT
    Summary
    Non-catalytic subunit common to nuclear DNA-dependent RNA polymerases II, IV and V; homologous to budding yeast RPB11 and the E. oli RNA polymerase alpha subunit.
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    Genomic context

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    See NRPB11 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    6
    Sequence:
    Chromosome: 3; NC_003074.8 (19317737..19319123, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein Neighboring gene ncRNA Neighboring gene RNA/RNP complex-1-interacting phosphatase Neighboring gene uncharacterized protein Neighboring gene cation/hydrogen exchanger 28 Neighboring gene RING/FYVE/PHD-type zinc finger family protein Neighboring gene DIS3-exonuclease-like protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Association between 36- and 13.6-kDa alpha-like subunits of Arabidopsis thaliana RNA polymerase II. Ulmasov T, et al. J Biol Chem, 1996 Mar 1. PMID 8617787
    2. Domains rearranged methyltransferase3 controls DNA methylation and regulates RNA polymerase V transcript abundance in Arabidopsis. Zhong X, et al. Proc Natl Acad Sci U S A, 2015 Jan 20. PMID 25561521, Free PMC Article
    3. SHH1, a homeodomain protein required for DNA methylation, as well as RDR2, RDM4, and chromatin remodeling factors, associate with RNA polymerase IV. Law JA, et al. PLoS Genet, 2011 Jul. PMID 21811420, Free PMC Article
    4. Subunit compositions of the RNA-silencing enzymes Pol IV and Pol V reveal their origins as specialized forms of RNA polymerase II. Ream TS, et al. Mol Cell, 2009 Jan 30. PMID 19110459, Free PMC Article
    5. Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana. Van Leene J, et al. Mol Syst Biol, 2010 Aug 10. PMID 20706207, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001203135.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-directed 5'-3' RNA polymerase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables RNA polymerase II activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of RNA polymerase II, core complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of RNA polymerase II, core complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    part_of RNA polymerase IV complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of RNA polymerase V complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    DNA-directed RNA polymerase, RBP11-like protein
    NP_001190064.1
    • NRPB11; FUNCTIONS IN: DNA-directed RNA polymerase activity, DNA binding; INVOLVED IN: transcription; LOCATED IN: DNA-directed RNA polymerase V complex, DNA-directed RNA polymerase II, holoenzyme, DNA-directed RNA polymerase II, core complex, DNA-directed RNA polymerase IV complex; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site (InterPro:IPR008193), DNA-directed RNA polymerase, dimerisation (InterPro:IPR011261), DNA-directed RNA polymerase, RBP11-like (InterPro:IPR009025).
    NP_190777.1
    • NRPB11; FUNCTIONS IN: DNA-directed RNA polymerase activity, DNA binding; INVOLVED IN: transcription; LOCATED IN: DNA-directed RNA polymerase V complex, DNA-directed RNA polymerase II, holoenzyme, DNA-directed RNA polymerase II, core complex, DNA-directed RNA polymerase IV complex; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site (InterPro:IPR008193), DNA-directed RNA polymerase, dimerisation (InterPro:IPR011261), DNA-directed RNA polymerase, RBP11-like (InterPro:IPR009025); BEST Arabidopsis thaliana protein match is: RNApolymerase 14 kDa subunit (TAIR:AT2G29540.2); Has 990 Blast hits to 990 proteins in 256 species: Archae - 62; Bacteria - 0; Metazoa - 336; Fungi - 323; Plants - 106; Viruses - 0; Other Eukaryotes - 163 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      19317737..19319123 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115068.5 → NP_190777.1  DNA-directed RNA polymerase, RBP11-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190777.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q38859
      UniProtKB/TrEMBL
      A0A178VE18, A0A5S9XKT2
      Conserved Domains (1) summary
      cd06926
      Location:13 → 105
      RNAP_II_RPB11; RPB11 subunit of Eukaryotic RNA polymerase II

    2. NM_001203135.1 → NP_001190064.1  DNA-directed RNA polymerase, RBP11-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190064.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4J5R0
      Conserved Domains (1) summary
      cd06926
      Location:13 → 135
      RNAP_II_RPB11; RPB11 subunit of Eukaryotic RNA polymerase II
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q38859.1

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