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    Tetratricopeptide repeat (TPR)-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825308, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Tetratricopeptide repeat (TPR)-like superfamily protein
    Primary source
    TAIR:AT3G61360
    Locus tag
    AT3G61360
    See related
    Araport:AT3G61360
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    1
    Sequence:
    Chromosome: 3; NC_003074.8 (22704304..22706141, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene F-box and associated interaction domains-containing protein Neighboring gene ncRNA Neighboring gene SKP1 interacting partner 4 Neighboring gene ncRNA Neighboring gene pre-mRNA-splicing factor CWC22-like protein (DUF3245) Neighboring gene ncRNA Neighboring gene Phosphatidylinositol N-acetyglucosaminlytransferase subunit P-like protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transformation of nad7 into the nuclear genome rescues the slow growth3 mutant in Arabidopsis. Hsieh WY, et al. RNA Biol, 2018. PMID 30422048, Free PMC Article
    2. The SLOW GROWTH3 Pentatricopeptide Repeat Protein Is Required for the Splicing of Mitochondrial NADH Dehydrogenase Subunit7 Intron 2 in Arabidopsis. Hsieh WY, et al. Plant Physiol, 2015 Jun. PMID 25888618, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. we have used slo3 as an example to demonstrate that transformation of correctly spliced nad7 into the nuclear genome and targeting the Nad7 subunit into mitochondria can restore complex I activity and plant phenotypes in the mutant
      Title: Transformation of nad7 into the nuclear genome rescues the slow growth3 mutant in Arabidopsis.
    2. the SLO3 pentatricopeptide repeat protein is a splicing factor of nad7 intron 2 in Arabidopsis mitochondria.[SLO3] [SLOW GROWTH3]
      Title: The SLOW GROWTH3 Pentatricopeptide Repeat Protein Is Required for the Splicing of Mitochondrial NADH Dehydrogenase Subunit7 Intron 2 in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    NM_116000.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within mRNA splicing, via spliceosome IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Tetratricopeptide repeat (TPR)-like superfamily protein
    NP_191695.1
    • Tetratricopeptide repeat (TPR)-like superfamily protein; CONTAINS InterPro DOMAIN/s: Pentatricopeptide repeat (InterPro:IPR002885); BEST Arabidopsis thaliana protein match is: Pentatricopeptide repeat (PPR) superfamily protein (TAIR:AT1G02420.1); Has 25235 Blast hits to 10240 proteins in 263 species: Archae - 1; Bacteria - 29; Metazoa - 217; Fungi - 376; Plants - 23987; Viruses - 0; Other Eukaryotes - 625 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      22704304..22706141 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116000.1 → NP_191695.1  Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191695.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M2C8
      UniProtKB/TrEMBL
      A0A5S9XNJ4
      Conserved Domains (5) summary
      COG0457
      Location:73 → 235
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      TIGR00756
      Location:317 → 350
      PPR; pentatricopeptide repeat domain (PPR motif)
      sd00004
      Location:179 → 205
      PPR; PPR repeat [structural motif]
      pfam12854
      Location:239 → 271
      PPR_1; PPR repeat
      pfam13041
      Location:208 → 257
      PPR_2; PPR repeat family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M2C8.1

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