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    PBB2 20S proteasome beta subunit PBB2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834056, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PBB2
    Official Full Name
    20S proteasome beta subunit PBB2
    Primary source
    TAIR:AT5G40580
    Locus tag
    AT5G40580
    See related
    Araport:AT5G40580
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    20S proteasome beta subunit PBB2; 20S PROTEASOME BETA SUBUNIT PBB2; MNF13.100; MNF13_100
    Summary
    Encodes 20S proteasome beta subunit PBB2 (PBB2).
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    Genomic context

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    See PBB2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    10
    Sequence:
    Chromosome: 5; NC_003076.8 (16248286..16250925, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene SGF29 tudor-like domain-containing protein Neighboring gene protease Do-like protein Neighboring gene Surfeit locus protein 2 (SURF2) Neighboring gene Cysteine/Histidine-rich C1 domain family protein Neighboring gene bromodomain testis-specific protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular organization of the 20S proteasome gene family from Arabidopsis thaliana. Fu H, et al. Genetics, 1998 Jun. PMID 9611183, Free PMC Article
    2. The 20S proteasome gene family in Arabidopsis thaliana. Parmentier Y, et al. FEBS Lett, 1997 Oct 27. PMID 9373170
    3. Structure and functional analysis of the 26S proteasome subunits from plants. Fu H, et al. Mol Biol Rep, 1999 Apr. PMID 10363660
    4. Affinity purification of the Arabidopsis 26 S proteasome reveals a diverse array of plant proteolytic complexes. Book AJ, et al. J Biol Chem, 2010 Aug 13. PMID 20516081, Free PMC Article
    5. Proteomic analysis of the 26S proteasome reveals its direct interaction with transit peptides of plastid protein precursors for their degradation. Sako K, et al. J Proteome Res, 2014 Jul 3. PMID 24846764

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001203514.2
    NM_001344344.1
    NM_180777.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables threonine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis involved in protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plastid HDA PubMed 
    part_of proteasome complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of proteasome core complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of proteasome core complex TAS
    Traceable Author Statement
    more info
    		 PubMed 
    part_of proteasome core complex, beta-subunit complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    20S proteasome beta subunit PBB2
    NP_001318715.1
    • 20S proteasome beta subunit PBB2 (PBB2); FUNCTIONS IN: peptidase activity, endopeptidase activity, threonine-type endopeptidase activity; INVOLVED IN: ubiquitin-dependent protein catabolic process; LOCATED IN: proteasome core complex, proteasome complex; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase T1A, proteasome beta-subunit (InterPro:IPR000243), Proteasome, subunit alpha/beta (InterPro:IPR001353); BEST Arabidopsis thaliana protein match is: N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein (TAIR:AT3G27430.3).
    NP_198874.1
    • 20S proteasome beta subunit PBB2 (PBB2); FUNCTIONS IN: peptidase activity, endopeptidase activity, threonine-type endopeptidase activity; INVOLVED IN: ubiquitin-dependent protein catabolic process; LOCATED IN: proteasome core complex, proteasome complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Proteasome, beta-type subunit, conserved site (InterPro:IPR016050), Peptidase T1A, proteasome beta-subunit (InterPro:IPR000243), Proteasome, subunit alpha/beta (InterPro:IPR001353); BEST Arabidopsis thaliana protein match is: N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein (TAIR:AT3G27430.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
    NP_851108.1
    • 20S proteasome beta subunit PBB2 (PBB2); FUNCTIONS IN: peptidase activity, endopeptidase activity, threonine-type endopeptidase activity; INVOLVED IN: ubiquitin-dependent protein catabolic process; LOCATED IN: proteasome core complex, proteasome complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Proteasome, beta-type subunit, conserved site (InterPro:IPR016050), Peptidase T1A, proteasome beta-subunit (InterPro:IPR000243), Proteasome, subunit alpha/beta (InterPro:IPR001353); BEST Arabidopsis thaliana protein match is: N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein (TAIR:AT3G27430.2); Has 6316 Blast hits to 6315 proteins in 595 species: Archae - 876; Bacteria - 488; Metazoa - 2055; Fungi - 1308; Plants - 688; Viruses - 0; Other Eukaryotes - 901 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      16248286..16250925 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123422.4 → NP_198874.1  20S proteasome beta subunit PBB2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_198874.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23709, Q7DLS1, Q8LAK8, Q8RWL9
      UniProtKB/TrEMBL
      A0A178UKG7, A0A5S9YAS3, A0A7G2FCM2
      Conserved Domains (1) summary
      cd03763
      Location:40 → 228
      proteasome_beta_type_7; proteasome beta type-7 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...

    2. NM_180777.3 → NP_851108.1  20S proteasome beta subunit PBB2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851108.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23709, Q7DLS1, Q8LAK8, Q8RWL9
      UniProtKB/TrEMBL
      A0A178UKG7, A0A5S9YAS3, A0A7G2FCM2
      Conserved Domains (1) summary
      cd03763
      Location:40 → 228
      proteasome_beta_type_7; proteasome beta type-7 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...

    3. NM_001344344.1 → NP_001318715.1  20S proteasome beta subunit PBB2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2FCM2, F4KIN7

    4. NM_001203514.2 → NP_001190443.1  20S proteasome beta subunit PBB2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190443.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2FCM2, F4KIN7
      Conserved Domains (2) summary
      COG0638
      Location:37 → 214
      PRE1; 20S proteasome, alpha and beta subunits [Posttranslational modification, protein turnover, chaperones]
      cd03763
      Location:40 → 222
      proteasome_beta_type_7; proteasome beta type-7 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7DLS1.2

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