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    AAO2 aldehyde oxidase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 823457, updated on 2-Oct-2024

    Summary

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    Official Symbol
    AAO2
    Official Full Name
    aldehyde oxidase 2
    Primary source
    TAIR:AT3G43600
    Locus tag
    AT3G43600
    See related
    Araport:AT3G43600
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    aldehyde oxidase 2; ALDEHYDE OXIDASE 2; aldehyde oxidase 3; Aldehyde oxidase gamma; AO3; AOgamma; Arabidopsis thaliana aldehyde oxidase 2; Arabidopsis thaliana aldehyde oxidase 3; atAO-2; AtAO3
    Summary
    Encodes an aldehyde oxidase. AAO2 does not appear to act on abscisic aldehyde in vitro but it is possible that it may function in abscisic acid biosynthesis when the activity of At2g27150 (AAO3), the primary abscisic aldehyde oxidase, is lost.
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    Genomic context

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    See AAO2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Sequence:
    Chromosome: 3; NC_003074.8 (15511832..15517545, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene zinc knuckle (CCHC-type) family protein Neighboring gene Spc97 / Spc98 family of spindle pole body (SBP) component Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. AAO2 impairment enhances aldehyde detoxification by AAO3 in Arabidopsis leaves exposed to UV-C or Rose-Bengal. Nurbekova Z, et al. Plant J, 2024 Oct. PMID 39190782
    2. Functional expression of two Arabidopsis aldehyde oxidases in the yeast Pichia pastoris. Koiwai H, et al. J Biochem, 2000 Apr. PMID 10739959
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AAO2 impairment enhances aldehyde detoxification by AAO3 in Arabidopsis leaves exposed to UV-C or Rose-Bengal.
      Title: AAO2 impairment enhances aldehyde detoxification by AAO3 in Arabidopsis leaves exposed to UV-C or Rose-Bengal.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_114228.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables FAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables aldehyde oxidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables indole-3-acetaldehyde oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    aldehyde oxidase 2
    NP_189946.1
    • aldehyde oxidase 2 (AAO2); FUNCTIONS IN: aldehyde oxidase activity; INVOLVED IN: oxidation reduction; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldehyde oxidase/xanthine dehydrogenase (InterPro:IPR016208), Ferredoxin (InterPro:IPR001041), Molybdopterin dehydrogenase, FAD-binding (InterPro:IPR002346), [2Fe-2S]-binding (InterPro:IPR002888), FAD-binding, type 2 (InterPro:IPR016166), CO dehydrogenase flavoprotein, C-terminal (InterPro:IPR005107), 2Fe-2S ferredoxin, iron-sulphur binding site (InterPro:IPR006058), CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 (InterPro:IPR016169), Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead (InterPro:IPR000674), Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding (InterPro:IPR008274); BEST Arabidopsis thaliana protein match is: aldehyde oxidase 1 (TAIR:AT5G20960.2); Has 18530 Blast hits to 17817 proteins in 1279 species: Archae - 421; Bacteria - 11000; Metazoa - 1023; Fungi - 117; Plants - 281; Viruses - 0; Other Eukaryotes - 5688 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      15511832..15517545 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114228.3 → NP_189946.1  aldehyde oxidase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_189946.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49156, O64418, Q7G192
      UniProtKB/TrEMBL
      A0A178VK44
      Conserved Domains (7) summary
      PLN00192
      Location:1 → 1317
      PLN00192; aldehyde oxidase
      cd00207
      Location:3 → 78
      fer2; 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis ...
      pfam00941
      Location:218 → 402
      FAD_binding_5; FAD binding domain in molybdopterin dehydrogenase
      pfam01315
      Location:568 → 678
      Ald_Xan_dh_C; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
      pfam01799
      Location:86 → 164
      Fer2_2; [2Fe-2S] binding domain
      pfam02738
      Location:699 → 1224
      Ald_Xan_dh_C2; Molybdopterin-binding domain of aldehyde dehydrogenase
      pfam03450
      Location:414 → 515
      CO_deh_flav_C; CO dehydrogenase flavoprotein C-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7G192.2

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