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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_000839.5 → NP_000830.2 metabotropic glutamate receptor 2 isoform a precursor
See identical proteins and their annotated locations for NP_000830.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (a).
- Source sequence(s)
-
AC099050, AK315816, BC041447, DA528713
- Consensus CDS
-
CCDS2834.1
- UniProtKB/Swiss-Prot
- B0M0K7, Q14416, Q14CU5, Q52MC6, Q9H3N6
- UniProtKB/TrEMBL
- A8K1R9, B0AZM5
- Related
- ENSP00000378492.3, ENST00000395052.8
- Conserved Domains (4) summary
-
- cd06375
Location:30 → 480
- PBP1_mGluR_groupII; Ligand binding domain of the group II metabotropic glutamate receptor
- pfam00003
Location:579 → 816
- 7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
- pfam01094
Location:60 → 456
- ANF_receptor; Receptor family ligand binding region
- pfam07562
Location:498 → 545
- NCD3G; Nine Cysteines Domain of family 3 GPCR
-
NM_001349116.2 → NP_001336045.1 metabotropic glutamate receptor 2 isoform c
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (c) is shorter at the N-terminus compared to isoform a.
- Source sequence(s)
-
AC099050
- UniProtKB/TrEMBL
-
Q86YG3
- Conserved Domains (4) summary
-
- pfam07562
Location:120 → 168
- NCD3G; Nine Cysteines Domain of family 3 GPCR
- cd14964
Location:189 → 213
- 7tm_GPCRs; TM helix 1 [structural motif]
- cl10011
Location:1 → 102
- Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
- cl28897
Location:188 → 441
- 7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
-
NM_001349117.2 → NP_001336046.1 metabotropic glutamate receptor 2 isoform d
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) contains an alternate internal exon compared to variant 1. The resulting isoform (d) has a shorter and distinct N-terminus compared to isoform a.
- Source sequence(s)
-
AC099050, AK313056, BC041447, DA528713
- UniProtKB/TrEMBL
-
Q86YG3
- Conserved Domains (4) summary
-
- pfam07562
Location:99 → 149
- NCD3G; Nine Cysteines Domain of family 3 GPCR
- cd14964
Location:169 → 194
- 7tm_GPCRs; TM helix 1 [structural motif]
- cl10011
Location:29 → 83
- Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily
- cl28897
Location:169 → 422
- 7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
RNA
-
NR_146059.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks two alternate exons compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
- Source sequence(s)
-
AC099050, BC041447, DA528713
- Related
-
ENST00000475478.5
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000003.12 Reference GRCh38.p14 Primary Assembly
- Range
-
51707068..51718613
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011533636.2 → XP_011531938.1 metabotropic glutamate receptor 2 isoform X3
- Conserved Domains (3) summary
-
- pfam00003
Location:397 → 634
- 7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
- pfam07562
Location:316 → 363
- NCD3G; Nine Cysteines Domain of family 3 GPCR
- cl10011
Location:30 → 298
- Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
-
XM_017006271.2 → XP_016861760.1 metabotropic glutamate receptor 2 isoform X1
- UniProtKB/Swiss-Prot
- B0M0K7, Q14416, Q14CU5, Q52MC6, Q9H3N6
- UniProtKB/TrEMBL
- A8K1R9, B0AZM5
- Conserved Domains (4) summary
-
- cd06375
Location:30 → 480
- PBP1_mGluR_groupII; Ligand binding domain of the group II metabotropic glutamate receptor
- pfam00003
Location:579 → 816
- 7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
- pfam01094
Location:60 → 456
- ANF_receptor; Receptor family ligand binding region
- pfam07562
Location:498 → 545
- NCD3G; Nine Cysteines Domain of family 3 GPCR
-
XM_047448047.1 → XP_047304003.1 metabotropic glutamate receptor 2 isoform X2
- UniProtKB/TrEMBL
- A8K1R9, B0AZM5
-
XM_011533642.2 → XP_011531944.1 metabotropic glutamate receptor 2 isoform X5
- Conserved Domains (2) summary
-
- cd06375
Location:30 → 470
- PBP1_mGluR_groupII; Ligand binding domain of the group II metabotropic glutamate receptor
- pfam01094
Location:60 → 456
- ANF_receptor; Receptor family ligand binding region
-
XM_024453490.2 → XP_024309258.1 metabotropic glutamate receptor 2 isoform X7
- UniProtKB/TrEMBL
-
H7BXL3
- Related
- ENSP00000296479.5, ENST00000296479.9
- Conserved Domains (1) summary
-
- cl10011
Location:30 → 429
- Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
-
XM_047448051.1 → XP_047304007.1 metabotropic glutamate receptor 2 isoform X4
-
XM_047448048.1 → XP_047304004.1 metabotropic glutamate receptor 2 isoform X4
-
XM_047448049.1 → XP_047304005.1 metabotropic glutamate receptor 2 isoform X4
-
XM_047448050.1 → XP_047304006.1 metabotropic glutamate receptor 2 isoform X4
-
XM_011533637.2 → XP_011531939.1 metabotropic glutamate receptor 2 isoform X4
See identical proteins and their annotated locations for XP_011531939.1
- Conserved Domains (4) summary
-
- pfam00003
Location:385 → 622
- 7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
- pfam01094
Location:1 → 262
- ANF_receptor; Receptor family ligand binding region
- pfam07562
Location:304 → 351
- NCD3G; Nine Cysteines Domain of family 3 GPCR
- cl10011
Location:1 → 286
- Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
-
XM_011533643.2 → XP_011531945.1 metabotropic glutamate receptor 2 isoform X6
- Conserved Domains (2) summary
-
- pfam00003
Location:147 → 384
- 7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
- pfam07562
Location:69 → 113
- NCD3G; Nine Cysteines Domain of family 3 GPCR
Alternate T2T-CHM13v2.0
Genomic
-
NC_060927.1 Alternate T2T-CHM13v2.0
- Range
-
51738578..51751605
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054346368.1 → XP_054202343.1 metabotropic glutamate receptor 2 isoform X2
- UniProtKB/TrEMBL
- A8K1R9, B0AZM5
-
XM_054346369.1 → XP_054202344.1 metabotropic glutamate receptor 2 isoform X3
-
XM_054346367.1 → XP_054202342.1 metabotropic glutamate receptor 2 isoform X1
- UniProtKB/Swiss-Prot
- B0M0K7, Q14416, Q14CU5, Q52MC6, Q9H3N6
- UniProtKB/TrEMBL
- A8K1R9, B0AZM5
-
XM_054346375.1 → XP_054202350.1 metabotropic glutamate receptor 2 isoform X5
-
XM_054346377.1 → XP_054202352.1 metabotropic glutamate receptor 2 isoform X7
- UniProtKB/TrEMBL
-
H7BXL3
-
XM_054346374.1 → XP_054202349.1 metabotropic glutamate receptor 2 isoform X4
-
XM_054346371.1 → XP_054202346.1 metabotropic glutamate receptor 2 isoform X4
-
XM_054346372.1 → XP_054202347.1 metabotropic glutamate receptor 2 isoform X4
-
XM_054346373.1 → XP_054202348.1 metabotropic glutamate receptor 2 isoform X4
-
XM_054346370.1 → XP_054202345.1 metabotropic glutamate receptor 2 isoform X4
-
XM_054346376.1 → XP_054202351.1 metabotropic glutamate receptor 2 isoform X6