U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    TRIQK triple QxxK/R motif containing [ Homo sapiens (human) ]

    Gene ID: 286144, updated on 27-Nov-2024

    Summary

    Official Symbol
    TRIQKprovided by HGNC
    Official Full Name
    triple QxxK/R motif containingprovided by HGNC
    Primary source
    HGNC:HGNC:27828
    See related
    Ensembl:ENSG00000205133 AllianceGenome:HGNC:27828
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C8orf83; PRO0845; UPF0599
    Summary
    Predicted to be located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in adrenal (RPKM 10.3), thyroid (RPKM 9.6) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See TRIQK in Genome Data Viewer
    Location:
    8q22.1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (92883534..93017665, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (94008453..94091047, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (93895762..93978372, complement)

    Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC441369 Neighboring gene uncharacterized LOC124901978 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27616 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19356 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:93986327-93986595 Neighboring gene interferon regulatory factor 5 pseudogene 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:94050860-94051674 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27617 Neighboring gene microRNA 8084 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr8:94146448-94147647 Neighboring gene long intergenic non-protein coding RNA 2906 Neighboring gene uncharacterized LOC105375644

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ40637, DKFZp779L1068

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    triple QxxK/R motif-containing protein
    Names
    protein TRIQK
    triple repetitive-sequence of QXXK/R protein homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001171795.2NP_001165266.1  triple QxxK/R motif-containing protein

      See identical proteins and their annotated locations for NP_001165266.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1-7 all encode the same protein.
      Source sequence(s)
      BC110326, BQ009934, BX474727
      Consensus CDS
      CCDS55261.1
      UniProtKB/Swiss-Prot
      Q629K1
      Related
      ENSP00000430837.1, ENST00000518748.5
      Conserved Domains (1) summary
      pfam15168
      Location:152
      TRIQK; Triple QxxK/R motif-containing protein family
    2. NM_001171796.2NP_001165267.1  triple QxxK/R motif-containing protein

      See identical proteins and their annotated locations for NP_001165267.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1-7 all encode the same protein.
      Source sequence(s)
      BC031029, BC110326, BQ009934, DA093687
      Consensus CDS
      CCDS55261.1
      UniProtKB/Swiss-Prot
      Q629K1
      Related
      ENSP00000368138.5, ENST00000378861.9
      Conserved Domains (1) summary
      pfam15168
      Location:152
      TRIQK; Triple QxxK/R motif-containing protein family
    3. NM_001171797.2NP_001165268.1  triple QxxK/R motif-containing protein

      See identical proteins and their annotated locations for NP_001165268.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1-7 all encode the same protein.
      Source sequence(s)
      BC110326, BQ009934, DA093687, DQ351291
      Consensus CDS
      CCDS55261.1
      UniProtKB/Swiss-Prot
      Q629K1
      Related
      ENSP00000429517.1, ENST00000521988.6
      Conserved Domains (1) summary
      pfam15168
      Location:152
      TRIQK; Triple QxxK/R motif-containing protein family
    4. NM_001171798.2NP_001165269.1  triple QxxK/R motif-containing protein

      See identical proteins and their annotated locations for NP_001165269.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1. Variants 1-7 all encode the same protein.
      Source sequence(s)
      AK097956, BC110326, BQ009934, DA093687
      Consensus CDS
      CCDS55261.1
      UniProtKB/Swiss-Prot
      Q629K1
      Related
      ENSP00000428822.1, ENST00000520430.5
      Conserved Domains (1) summary
      pfam15168
      Location:152
      TRIQK; Triple QxxK/R motif-containing protein family
    5. NM_001171799.2NP_001165270.1  triple QxxK/R motif-containing protein

      See identical proteins and their annotated locations for NP_001165270.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR, compared to variant 1. Variants 1-7 all encode the same protein.
      Source sequence(s)
      BC110326, BQ009934, DA191587
      Consensus CDS
      CCDS55261.1
      UniProtKB/Swiss-Prot
      Q629K1
      Related
      ENSP00000442030.1, ENST00000537541.1
      Conserved Domains (1) summary
      pfam15168
      Location:152
      TRIQK; Triple QxxK/R motif-containing protein family
    6. NM_001191035.2NP_001177964.1  triple QxxK/R motif-containing protein

      See identical proteins and their annotated locations for NP_001177964.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR, compared to variant 1. Variants 1-7 all encode the same protein.
      Source sequence(s)
      AC027242, AC117834, BQ009934, CB989812
      Consensus CDS
      CCDS55261.1
      UniProtKB/Swiss-Prot
      Q629K1
      Related
      ENSP00000429742.1, ENST00000524107.5
      Conserved Domains (1) summary
      pfam15168
      Location:152
      TRIQK; Triple QxxK/R motif-containing protein family
    7. NM_001191036.2NP_001177965.1  triple QxxK/R motif-containing protein

      See identical proteins and their annotated locations for NP_001177965.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR, compared to variant 1. Variants 1-7 all encode the same protein.
      Source sequence(s)
      AC027242, AC117834, BQ009934, DA115453
      Consensus CDS
      CCDS55261.1
      UniProtKB/Swiss-Prot
      Q629K1
      Related
      ENSP00000429381.1, ENST00000519969.5
      Conserved Domains (1) summary
      pfam15168
      Location:152
      TRIQK; Triple QxxK/R motif-containing protein family

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

      Range
      92883534..93017665 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047421713.1XP_047277669.1  triple QxxK/R motif-containing protein isoform X1

      UniProtKB/Swiss-Prot
      Q629K1
    2. XM_017013350.2XP_016868839.1  triple QxxK/R motif-containing protein isoform X1

      UniProtKB/Swiss-Prot
      Q629K1
      Related
      ENSP00000430992.1, ENST00000521617.5
      Conserved Domains (1) summary
      pfam15168
      Location:152
      TRIQK; Triple QxxK/R motif-containing protein family
    3. XM_017013347.2XP_016868836.1  triple QxxK/R motif-containing protein isoform X1

      UniProtKB/Swiss-Prot
      Q629K1
      Conserved Domains (1) summary
      pfam15168
      Location:152
      TRIQK; Triple QxxK/R motif-containing protein family
    4. XM_047421711.1XP_047277667.1  triple QxxK/R motif-containing protein isoform X1

      UniProtKB/Swiss-Prot
      Q629K1
    5. XM_024447136.2XP_024302904.1  triple QxxK/R motif-containing protein isoform X1

      UniProtKB/Swiss-Prot
      Q629K1
      Conserved Domains (1) summary
      pfam15168
      Location:152
      TRIQK; Triple QxxK/R motif-containing protein family
    6. XM_047421712.1XP_047277668.1  triple QxxK/R motif-containing protein isoform X1

      UniProtKB/Swiss-Prot
      Q629K1
    7. XM_017013349.2XP_016868838.1  triple QxxK/R motif-containing protein isoform X1

      UniProtKB/Swiss-Prot
      Q629K1
      Conserved Domains (1) summary
      pfam15168
      Location:152
      TRIQK; Triple QxxK/R motif-containing protein family

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060932.1 Alternate T2T-CHM13v2.0

      Range
      94008453..94091047 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054360331.1XP_054216306.1  triple QxxK/R motif-containing protein isoform X1

      UniProtKB/Swiss-Prot
      Q629K1
    2. XM_054360327.1XP_054216302.1  triple QxxK/R motif-containing protein isoform X1

      UniProtKB/Swiss-Prot
      Q629K1
    3. XM_054360328.1XP_054216303.1  triple QxxK/R motif-containing protein isoform X1

      UniProtKB/Swiss-Prot
      Q629K1
    4. XM_054360330.1XP_054216305.1  triple QxxK/R motif-containing protein isoform X1

      UniProtKB/Swiss-Prot
      Q629K1
    5. XM_054360329.1XP_054216304.1  triple QxxK/R motif-containing protein isoform X1

      UniProtKB/Swiss-Prot
      Q629K1
    6. XM_054360332.1XP_054216307.1  triple QxxK/R motif-containing protein isoform X1

      UniProtKB/Swiss-Prot
      Q629K1