Tti2 TELO2 interacting protein 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Tti2provided by RGD
Official Full Name: TELO2 interacting protein 2provided by RGD
Primary source: RGD:1310414
See related: EnsemblRapid:ENSRNOG00000023494 AllianceGenome:RGD:1310414
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1310414
Summary: Predicted to be part of TTT Hsp90 cochaperone complex. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 39. Orthologous to human TTI2 (TELO2 interacting protein 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 93.2), Spleen (RPKM 76.2) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 16q12.3

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	16	NC_086034.1 (67683721..67692881, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	16	NC_051351.1 (60980665..60988587, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	16	NC_005115.4 (64737342..64745207, complement)

Chromosome 16 - NC_086034.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Systems genetics in the rat HXB/BXH family identifies Tti2 as a pleiotropic quantitative trait gene for adult hippocampal neurogenesis and serum glucose.
Title: Systems genetics in the rat HXB/BXH family identifies Tti2 as a pleiotropic quantitative trait gene for adult hippocampal neurogenesis and serum glucose.

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General gene information

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Markers

RH137307 (e-PCR)
- UniSTS:219395

RH142490 (e-PCR)
- UniSTS:231737

AW527757 (e-PCR)
- UniSTS:246076

BE099580 (e-PCR)
- UniSTS:260931

RH137645 (e-PCR)
- UniSTS:219732

RH135178 (e-PCR)
- UniSTS:218455

Gene Ontology Provided by RGD

Component	Evidence Code	Pubs
part_of TTT Hsp90 cochaperone complex	IBA Inferred from Biological aspect of Ancestor more info
part_of TTT Hsp90 cochaperone complex	IEA Inferred from Electronic Annotation more info
part_of TTT Hsp90 cochaperone complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: TELO2-interacting protein 2

Names: Tel2 interacting protein 2 homolog; uncharacterized protein C8orf41 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.