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    Tmem39a transmembrane protein 39a [ Rattus norvegicus (Norway rat) ]

    Gene ID: 288092, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tmem39aprovided by RGD
    Official Full Name
    transmembrane protein 39aprovided by RGD
    Primary source
    RGD:1306421
    See related
    EnsemblRapid:ENSRNOG00000003075 AllianceGenome:RGD:1306421
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1306421
    Summary
    Predicted to be involved in negative regulation of autophagosome assembly; negative regulation of autophagosome maturation; and positive regulation of viral genome replication. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human TMEM39A (transmembrane protein 39A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 71.5), Thymus (RPKM 70.1) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tmem39a in Genome Data Viewer
    Location:
    11q21
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (75666154..75695486, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (62160631..62189964, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (64723181..64752514, complement)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134481005 Neighboring gene Rho GTPase activating protein 31 Neighboring gene protein O-glucosyltransferase 1 Neighboring gene uncharacterized LOC103693581 Neighboring gene translocase of inner mitochondrial membrane domain containing 1

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in autophagy IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of autophagosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of autophagosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of autophagosome assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of autophagosome maturation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of autophagosome maturation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of autophagosome maturation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of viral genome replication ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013865.1NP_001013887.1  transmembrane protein 39A

      See identical proteins and their annotated locations for NP_001013887.1

      Status: PROVISIONAL

      Source sequence(s)
      BC085845
      UniProtKB/Swiss-Prot
      Q5U2V9
      UniProtKB/TrEMBL
      A6IR58
      Related
      ENSRNOP00000049087.3, ENSRNOT00000048738.6
      Conserved Domains (1) summary
      pfam10271
      Location:42475
      Tmp39; Putative transmembrane protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      75666154..75695486 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)