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    APG2 Sec-independent periplasmic protein translocase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 814640, updated on 18-Sep-2024

    Summary

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    Official Symbol
    APG2
    Official Full Name
    Sec-independent periplasmic protein translocase
    Primary source
    TAIR:AT2G01110
    Locus tag
    AT2G01110
    See related
    Araport:AT2G01110
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ALBINO AND PALE GREEN 2; F23H14.8; F23H14_8; PGA2; TATC; TWIN-ARGININE TRANSLOCATION C; UNE3; unfertilized embryo sac 3
    Summary
    mutant is Albino and pale green; Chloroplast Protein Translocation (tatC). Core subunit of the chloroplast Tat translocase. Integral chloroplast thylakoid membrane protein.
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    Genomic context

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    See APG2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    4
    Sequence:
    Chromosome: 2; NC_003071.7 (83260..85258, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family Neighboring gene Ubiquinol-cytochrome C reductase hinge protein Neighboring gene FAM133-like protein Neighboring gene ncRNA Neighboring gene origin recognition complex subunit 4 Neighboring gene DEA(D/H)-box RNA helicase family protein Neighboring gene Aldolase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Localization and integration of thylakoid protein translocase subunit cpTatC. Martin JR, et al. Plant J, 2009 Jun. PMID 19207210, Free PMC Article
    2. Sequence and phylogenetic analyses of the twin-arginine targeting (Tat) protein export system. Yen MR, et al. Arch Microbiol, 2002 Jun. PMID 12029389
    3. The Pentatricopeptide Repeat Protein MEF31 is Required for Editing at Site 581 of the Mitochondrial tatC Transcript and Indirectly Influences Editing at Site 586 of the Same Transcript. Arenas-M A, et al. Plant Cell Physiol, 2018 Feb 1. PMID 29216369
    4. Plant mitochondria contain the protein translocase subunits TatB and TatC. Carrie C, et al. J Cell Sci, 2016 Oct 15. PMID 27609835
    5. An essential role of a TatC homologue of a Delta pH- dependent protein transporter in thylakoid membrane formation during chloroplast development in Arabidopsis thaliana. Motohashi R, et al. Proc Natl Acad Sci U S A, 2001 Aug 28. PMID 11526245, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. MEF31 does not directly target site tatC-586, and only indirectly influences editing at this site.
      Title: The Pentatricopeptide Repeat Protein MEF31 is Required for Editing at Site 581 of the Mitochondrial tatC Transcript and Indirectly Influences Editing at Site 586 of the Same Transcript.
    2. mitochondrial-encoded TatC is a functional gene that is translated into a protein in the model plant Arabidopsis thaliana A TatB--like subunit localized to the inner membrane was also identified that is nuclear-encoded and is essential for plant growth and development.
      Title: Plant mitochondria contain the protein translocase subunits TatB and TatC.
    3. An approximately equimolar ratio of the TatB and TatC components was observed in tissues from Arabidopsis thaliana, whereas TatA was detectable only in minor amounts. [TatC]
      Title: Tat subunit stoichiometry in Arabidopsis thaliana challenges the proposed function of TatA as the translocation pore.
    4. Chloroplast TatC targets to thylakoid membranes via a stromal intermediate, and that cpTatC membrane integration is not altered by competition with precursors of the cpSec and cpTat pathways.
      Title: Localization and integration of thylakoid protein translocase subunit cpTatC.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_126173.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables proton motive force dependent protein transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within double fertilization forming a zygote and endosperm IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within thylakoid membrane organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of TAT protein transport complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast thylakoid membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of receptor complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in thylakoid membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Sec-independent periplasmic protein translocase
    NP_565252.1
    • ALBINO AND PALE GREEN 2 (APG2); FUNCTIONS IN: proton motive force dependent protein transmembrane transporter activity; INVOLVED IN: thylakoid membrane organization, double fertilization forming a zygote and endosperm; LOCATED IN: chloroplast thylakoid membrane, receptor complex, chloroplast, integral to thylakoid membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Sec-independent periplasmic protein translocase (InterPro:IPR002033), Sec-independent periplasmic protein translocase, conserved site (InterPro:IPR019820), Twin arginine-targeting protein translocase, TatC (InterPro:IPR019822); Has 5953 Blast hits to 5918 proteins in 1859 species: Archae - 177; Bacteria - 3492; Metazoa - 0; Fungi - 0; Plants - 81; Viruses - 0; Other Eukaryotes - 2203 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      83260..85258 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_126173.4 → NP_565252.1  Sec-independent periplasmic protein translocase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565252.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SJV5, Q9XFI4
      UniProtKB/TrEMBL
      A0A178VUB7, A0A5S9WW76, C0Z2T3
      Conserved Domains (1) summary
      TIGR00945
      Location:113 → 328
      tatC; Twin arginine targeting (Tat) protein translocase TatC
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SJV5.2

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